Genomic technologies have the potential to greatly increase the efficiency of the drug development process. As part of our tuberculosis drug discovery program, we used DNA microarray technology to profile drug-induced effects in Mycobacterium tuberculosis. Expression profiles of M. tuberculosis treated with compounds that inhibit key metabolic pathways are required as references for the assessm...

349 THE CORRELATION OF CERVICAL INTRAEPITHELIAL NEOPLASIA 3 DETECTED BY CERVICAL PUNCH BIOPSIES WITH THE PATHOLOGIC RESULTS OF CONIZATION AND HYSTERECTOMY Ki-Won Kim, MD, Kyoung-Mi Kim, MD, Jung-Woo Park, MD, Hyun-Jae Jung, MD, Jee-Young Han, MD, Joon-Mee Kim, MD, Jee-Hyun Park, MD, Sung-Ook Hwang, MD, Woo-Young Lee, MD, Eunseop Song, MD Departments of Obstetrics and Gynecology, Pathology, Inha...

Novel mutations in NADH dehydrogenase (ndh) were detected in 8 of 84 (9.5%) isoniazid (INH)-resistant isolates (T110A [n = 1], R268H [n = 7]), but not in 22 INH-susceptible isolates of Mycobacterium tuberculosis. Significantly, all eight isolates with mutations at ndh did not have mutations at katG, kasA, or the promoter regions of inhA or ahpC, except for one isolate. Mutations in ndh appear t...

Recently, the demand for floating solar power farms in lakes and coasts (rather than on land) has been increasing rapidly. It is important to develop a numerical analysis technique that considers environmental conditions predict structural stability accurate motion response while designing farm. In this study, we performed comparison under similar those of Inha University towing tank (IUTT) mod...

Quanli Hu, Ok Hyoung Lee, Yun Soo Lim, Yong-Sang Kim, Ju Kyung Shin, Sung-Hyeon Baeck, Hyun Ho Lee, Hyun-Mi Kim, Ki-Bum Kim, and Tae-Sik Yoon Department of Nano Science and Engineering, Myongji University, Yongin, Gyeonggi-do 449-728, Korea Department of Chemical and Engineering, Inha University, Incheon 402-751, Korea Department of Chemical and Engineering, Myongji University, Yongin, Gyeonggi...

Sequence analyses of 74 strains that encompassed major phylogenetic lineages of the Mycobacterium tuberculosis complex revealed 10 polymorphisms in mshA (Rv0486) and four polymorphisms in inhA (Rv1484) that were not responsible for isoniazid or prothionamide resistance. Instead, some of these mutations were phylogenetically informative. This genetic diversity must be taken into consideration fo...

1Department of Biological Engineering, College of Engineering, Inha University, Incheon 402-751, Republic of Korea 2Institute of Nano Electronic Engineering (INEE) and School of Bioprocess Engineering, Universiti Malaysia Perlis, 01000 Kangar, Perlis, Malaysia 3Department of Microbiology, Molecular Biology and Biotechnology, Himalayan College of Agricultural Sciences and Technology (HICAST), P....