نتایج جستجو برای: inherited neurodevelopmental disease

تعداد نتایج: 1517926  

2016
Tracy L. Bale

Prenatal insults, such as maternal stress, are associated with an increased neurodevelopmental disease risk and impact males significantly more than females, including increased rates of autism, mental retardation, stuttering, dyslexia, and attention deficit/hyperactivity disorder (ADHD). Sex differences in the placenta, which begin with sex chromosomes, are likely to produce sex-specific trans...

Journal: :Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2018
Milo R Smith Benjamin S Glicksberg Li Li Rong Chen Hirofumi Morishita Joel T Dudley

High and increasing prevalence of neurodevelopmental disorders place enormous personal and economic burdens on society. Given the growing realization that the roots of neurodevelopmental disorders often lie in early childhood, there is an urgent need to identify childhood risk factors. Neurodevelopment is marked by periods of heightened experience-dependent neuroplasticity wherein neural circui...

Journal: :Journal of medical genetics 2001
L Villard N Lévy F Xiang A Kpebe V Labelle C Chevillard Z Zhang C E Schwartz M Tardieu J Chelly M Anvret M Fontès

BACKGROUND Rett syndrome is a neurodevelopmental disorder affecting only girls; 99.5% of Rett syndrome cases are sporadic, although several familial cases have been reported. Mutations in the MECP2 gene were identified in approximately 70-80% of sporadic Rett syndrome cases. METHODS We have screened the MECP2 gene coding region for mutations in five familial cases of Rett syndrome and studied...

Journal: :Journal of Clinical Investigation 2019

Journal: :The Journal of Neuroscience 1982

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