Matrix Analysis of Corrosion Inhibition Phenomena (MACIP), in which an inhibitor isconsidered as a point in a multi-dimensional virtual efficiency space, was performed on somepyridine derivatives. The needed molecular parameters such as HOMO and LUMO energylevels, charge densities on hetero atom, dipole moment, heat of formation, and total energyvalues were obtained by means of semi-empirical q...

Screening in mixtures is a common approach for increasing the efficiency of high-throughput screening. Here we investigate how the "compound load" of mixtures influences promiscuous aggregate-based inhibition. We screened 764 molecules individually and in mixtures of 10 at 5 miccroM each, comparing the observed inhibition of the mixtures to that predicted from single-compound results. Synergist...

The inhibition of corrosion behaviour carbon steel in Well water has been studied by the anticorrosion natural Jeera dye (JD) and ZnSO4 system. Results Obtained Weight loss study shows 98% Maximum Inhibition efficiency at 10 ml Extract 50ppm ZnSO4. Synergistic parameters suggest that a synergistic effect existing between extract Zn2+.Statistical “F” test also revealed this effect. Surface analy...

Inhibition of Brd4 by JQ1 treatment showed potential in the treatment of glioma, however, some cases showed low sensitivity of JQ1. In addition, the pre-clinical analysis showed its limitation by demonstrating that transient treatment with JQ1 leads to aggressive tumor development. Thus, an improved understanding of the mechanisms underlying JQ1 is urgently required to design strategies to impr...

Human manganese superoxide dismutase is a mitochondrial metalloenzyme that is involved in protecting aerobic organisms against superoxide toxicity, and has been implicated in slowing tumor growth. Unfortunately, this enzyme exhibits strong product inhibition, which limits its potential biomedical applications. Previous efforts to alleviate human manganese superoxide dismutase product inhibition...

We developed a system that gave electrical stimulation with intensity in proportion to the voluntary EMG through the EMG recording electrodes, and used it for hemiplegic traning. The training effect was observed in long (a month of the training) and short (ten minutes after the training) period. We investigated this training effect of this system physiologically. We carried out two experiments;...

BACKGROUND The acid corrosion inhibition process of mild steel in 1 M HCl by 4-[(2-amino-1, 3, 4-thiadiazol-5-yl)methoxy]coumarin (ATC), has been investigated using weight loss technique and scanning electron microscopy (SEM). ATC was synthesized, and its chemical structure was elucidated and confirmed using spectroscopic techniques (infrared and nuclear magnetic resonance spectroscopy). FIND...

In this study, Zinc Oxide nanoparticles (ZnONPs) were synthesized by chemical method and their antibacterial efficiency against a clinical isolate of Staphylococcus aureus was studied. The Zinc Oxide nanoparticles have shown a commendable inhibition effect on the growth of most notorious bacterial pathogen S.aureus. The nanoparticles size and shapes were characterized by trans...