BACKGROUND Respiratory swallowing coordination is regarded as one of the several mechanisms by which the airway is protected from aspiration during swallowing. A lack of reciprocity between respiration and swallowing has been indicated as one of the mechanisms that can lead to aspiration and pneumonia. Since chronic obstructive pulmonary disease (COPD) is a pulmonary condition, we have hypothes...

BACKGROUND In healthy subjects deep inspiration transiently dilates the airways, while many asthmatic subjects show bronchoconstriction by a mechanism which is incompletely understood. We hypothesised that the negative intrathoracic pressure associated with deep inspiration occurring in the context of increased leakiness of the airway vasculature may temporarily increase airway oedema and thus ...

In the ever-expanding sea of scientific advances, how do you find inspiration for your own study? Cell editor Jiaying Tan talked with Mark Lemmon and Joseph (Yossi) Schlessinger about the importance of fueling your research creativity with the conceptual excitement and technical advance from the broad scientific field. An excerpt of the conversation appears below.

Designers immerse themselves in environments rich in inspiration. Previous research has tended to neglect the vital role of sources of inspiration in triggering and guiding designers’ activities. This paper reports research which investigates the gathering of inspiration sources and exploration of ideas and hence attempts to understand how inspiration is harnessed. We conducted a progressive se...

Impedance phlebography, a noninvasive approach to the diagnosis of venous thrombosis, depends on decreasing calf electrical impedance in normal subjects during inspiration. In order to assess the relationship between impedance changes and inspiratory volume, normal subjects were studied at various depths of inspiration. The mean inspiration volume required for a result indicating no evidence of...

Tracheal ultrasonography was performed to measure the width of the tracheal ring shadow and to assess the clinical relevance of these measurements for identifying tracheal collapse. The first tracheal ring width (FTRW) and thoracic inlet tracheal ring width (TITRW) were measured on both expiration and inspiration. The mean of the FTRW width (129 dogs) was greater in expiration (10.97 plusmn; 1....

When the presence of a non-opaque foreign body in a main or lower lobe bronchus is suspected, the following radiographs will be required, in addition to screening in order to note the positive movements of the mediastinum, heart and diaphragm: (1) A postero-anterior view at the end of inspiration; (2) a postero-anterior view at the end of expiration; (3) a lateral view; and (4) occasionally a b...

The inspiratory timing of lung crackles in patients with bronchiectasis was compared with the inspiratory timing of the lung crackles in chronic bronchitis and alveolitis. In severe obstructive chronic bronchitis the lung crackles are typically confined to early inspiration while in alveolitis the lung crackles continue to the end of inspiration but may begin in the early or the mid phase of in...