نتایج جستجو برای: instance reduction ir
تعداد نتایج: 629601 فیلتر نتایج به سال:
Binding of insulin receptor substrate proteins 1 and 2 (IRS1/2) to the insulin receptor (IR) is essential for the regulation of insulin sensitivity and energy homeostasis. However, the mechanism of IRS1/2 recruitment to the IR remains elusive. Here, we identify adaptor protein APPL1 as a critical molecule that promotes IRS1/2-IR interaction. APPL1 forms a complex with IRS1/2 under basal conditi...
Reduction of aldehydes and ketones to the corresponding alcohols in the presence of sodium cyanoborohdride as reductive agent and Tonsil clay as catalyst under solvent free conditions was investigated. Tonsil (catalyst) decreased the reduction time of each aldehyde and ketone to proportional alcohols in comparison with their reduction in the absence of catalyst with high degree purity of alcoho...
Supported Pd-based catalysts used in heterogeneously catalyzed liquid phase processes often undergo an activation step through reduction of the oxide or oxidic passivation layer prior to reaction. An oxidized Pd/Al2O3 catalyst was reduced by using H2-saturated cyclohexane at 70 °C, and followed real time attenuated total reflection infrared spectroscopy (ATR-IR), high-energy X-ray diffraction (...
The iridium(Ir) (triNHC = tri-N-heterocyclic carbene)-catalyzed transfer hydrogenation of glycerol carbonate (GC) is described in the absence additional hydride sources. reduction provides a sustainable route to produce industrially-valuable formate and lactate with high turnover numbers (TONs). bimetallic Ir(I) involving triNHC carbene ligands exhibits TONs, reaction mechanism, including Ir(tr...
INTRODUCTION The goal of this study was to investigate (1) the associations of rheumatoid arthritis (RA)-related inflammation or rheumatoid factor/anti-cyclic citrullinated peptide (anti-CCP) positivity with lipid profiles and insulin resistance (IR), (2) the effects of biologic therapy on lipid profiles and IR, and (3) potential predictors for the presence of subclinical atherosclerosis. MET...
1 Reminder: Polynomial Time Reductions and NP-completeness Polynomial-time reduction Definition 1. A polynomial-time reduction from a decision problem Π1 to a decision problem Π2 is a polynomialtime algorithm, which, for any instance of Π1 produces an equivalent instance of Π2. If there exists a polynomial-time reduction from Π1 to Π2, we say that Π1 is polynomial-time reducible to Π2 and write...
Multi-instance learning, as other machine learning tasks, also suffers from the curse of dimensionality. Although dimensionality reduction methods have been investigated for many years, multi-instance dimensionality reduction methods remain untouched. On the other hand, most algorithms in multi-instance framework treat instances in each bag as independently and identically distributed (i.i.d.) ...
Using evolutionary algorithms as instance selection for data reduction in KDD: an experimental study
Evolutionary algorithms are adaptive methods based on natural evolution that may be used for search and optimization. As data reduction in knowledge discovery in databases (KDDs) can be viewed as a search problem, it could be solved using evolutionary algorithms (EAs). In this paper, we have carried out an empirical study of the performance of four representative EA models in which we have take...
Multiple Instance Learning (MIL) proposes a new paradigm when instance labeling, in the learning step, is not possible or infeasible, by assigning a single label (positive or negative) to a set of instances called bag. In this paper, an operator based on homogeneity of positive bags for MIL is introduced. Our method consists in removing instances from the positives bags according to their simil...
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