The aim of this study was to compare lateral photon-electron (LPE), helical tomotherapy (HT), and volumetric-modulated arc therapy (VMAT) plans for total scalp irradiation. We selected a single adult model case and compared the dosimetric results for the three plans. All plans mainly used 6-MV photon beams, and the prescription dose was 60 Gy in 30 fractions. First, we compared the LPE, HT and ...

Background and Aim: To study compare the hemodynamic stability duration of analgesia in spinal anaesthesia among bolus versus lower fractional doses bupivacaine arachnoid block for patients undergoing abdominal surgeries specifically urologic, pelvic, limb surgeries. Methods: Interventional Randomized Comparative case-control done 70 participants to with under subarachnoid Results: sum up, we f...

Modification of recombinant human interleukin-2 (IL-2) with polyethylene glycol (PEG-IL-2) decreases clearance and might favor absorption into the lymphatics, due to its increased molecular weight. In the present study, we compared the plasma and lymph concentrations of IL-2 and PEG-IL-2 in Yorkshire pigs. The IL-2 regimens were i.v. bolus (0.1-1.6 x 10(6) I.U., MIU/kg), 15-min i.v. infusion (0...

An intermittent regimen of trimethoprim-sulfamethoxazole was tested in the corticosteroid-treated rat model to learn whether or not administration for 3 consecutive days a week would provide prophylaxis equal to continuous daily doses. Although all of the untreated control animals acquired Pneumocystis carinii pneumonia, none of the animals given either continuous or intermittent trimethoprim-s...

About 10% of patients in the intensive care unit which develop acute renal failure will depend on renal replacement therapy. Although there are no data showing reduction in mortality when compared with intermittent therapy, continuous therapies provide higher cumulative doses of dialysis and greater hemodynamic stability. However, have high costs and are not available in many centers. In this c...

Objectives: This study was carried out to compare intermittent bolus and continuous infusion for epidural labor analgesia in terms of total dose requirement local anesthetic quality as primary objective. Secondary objective level sensory block, motor hemodynamic variables, mode delivery, duration second stage, neonatal outcome, side effects, postpartum complications. Methods: Eighty women ASA p...

BACKGROUND Little is known about safety of and adherence to intermittent HIV PrEP regimens, which may be more feasible than daily dosing in some settings. We present safety and adherence data from the first trial of an intermittent PrEP regimen among Kenyan men who have sex with men (MSM) and female sex workers (FSW). METHODS/PRINCIPAL FINDINGS MSM and FSW were randomized to daily oral FTC/TD...

background: this study describes the possibility of implementing three-dimensional printing technology to create a precise construction of a planned bolus, based on computed tomography information stored in the digital imaging and communications in medicine (dicom) format file. materials and methods:  to create the bolus with a 3d printer, we converted data in the dicom format to the stereolith...