THE PHENOTYPIC CHARACTERIZATION of obstructive sleep apnea (OSA) continues to unfold. Recent studies provide evidence that this syndrome has the potential to disturb cardiovascular, neurological, and endocrine homeostatic processes (1, 6, 8, 9). Li et al. (5) present convincing evidence that long-term exposure to hypoxia-reoxygenation, modeling oxygenation patterns of severe sleep apnea, impair...

Oxygen fluctuations represent a common stressor in estuarine and intertidal environments and can compromise the mitochondrial integrity and function in marine organisms. We assessed the role of mitochondrial protection mechanisms (ATP-dependent and -independent mitochondrial proteases, and antioxidants) in tolerance to intermittent hypoxia or anoxia in three species of marine bivalves: hypoxia-...