Crohn's disease is an inflammatory intestinal disease that primarily causes abdominal pain and diarrhea. We report a male patient who presented with penile and scrotal lymphedema and inguinal fistulas as the first manifestations of Crohn's disease. Extraintestinal or metastatic Crohn's disease initially presenting as genital lymphedema with fistula formation is rare. Skin lesions in extraintest...

Among the extraintestinal manifestations of inflammatory bowel disease (IBD), pyoderma gangrenosum (PG) often poses a therapeutic challenge. We describe two cases of PG associated with inflammatory bowel disease, who responded to treatment with Infliximab. © 2011 Elsevier España, S.L. All rights reserved. Pioderma gangrenoso asociado a enfermedad inflamatoria intestinal. Descripción de 2 casos ...

Introduction: Crohn’s disease (CD) is classically described as a chronic granulomatous inflammatory bowel disease, laryngeal and other otolaryngologic manifestations of CD are uncommon and may be subtle, as laryngeal involvement by CD has been reported in only six cases in the medical literature. Objective: we describe a case of an Egyptian man with extra intestinal CD that involves the supragl...

Background and Aims: The diagnosis of Churg-Strauss syndrome (CSS), an allergic granulomatosis involving smalland medium-sized vessels, requires the presence of at least four of six criteria including asthma, peripheral eosinophilia, and systemic vasculitis. The gastrointestinal manifestations have never been reviewed. Methods: The 75 articles in the English literature found by electronic searc...

Inflammatory bowel disease (IBD) is a disease that affects the intestinal tract via an inflammatory process. Patients who suffer from IBD often have diseases that affect multiple other organ systems as well. These are called extraintestinal manifestations and can be just as, if not more debilitating than the intestinal inflammation itself. The skin is one of the most commonly affected organ sys...

OBJECTIVE To study the manifestations of arc of Riolan expansion (ARE) using multi-detector computed tomography angiography (MDCTA). MATERIALS AND METHODS The manifestations and clinical data of 626 consecutive mesentery CTA images were retrospectively analyzed. The 47 cases with ARE and 47 patients without expansion were involved. The average diameter of arc of Riolan was measured. Two radio...

Amebic colitis is a disease revealing diverse clinical manifestations and endoscopic gross features and often confused with other types of colitis. In case of misdiagnosis as an idiopathic inflammatory bowel disease or delayed recognition of intestinal amebiasis, an undesirable outcome may occur resulting from erroneous administration of steroids or delayed antiamebic treatment. To demonstrate ...

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) (or autoimmune polyendocrine syndrome type 1) is a rare autosomal recessive disorder caused by mutations in the autoimmune regulator gene. It causes a loss in central immune tolerance, failure to eliminate autoreactive T cells in the thymus, and their escape to the periphery. APECED patients are susceptible to mucocutaneous...

with small bowel sarcoidosis,3 the association between intestinal sarcoid and villous atrophy is unknown. Crohn's disease and sarcoidosis have common systemic manifestations, and the most frequently occurring cutaneous lesion to be associated with both conditions is erythema nodosum. However, cutaneous granulomas do occur in Crohn's disease, though rarely in areas which are not a direct extensi...