The membrane bilayer has a significant influence over the proteins embedded within it. G protein-coupled receptors (GPCRs) form a large group of membrane proteins with a vast array of critical functions, and direct and indirect interactions with the bilayer are thought to control various essential aspects of receptor function. The presence of cholesterol, in particular, has been the focus of a ...

A generation ago, a melding of imagination and experimental evidence led to the hypothesis that catecholamines were essential in establishing basal cardiac pacemaking rhythm. Subsequent discoveries of depolarizing "pacemaker" currents and viable adult catecholamine-deficient animals raised serious doubts about the necessity of catecholamines in pacemaking. However, the findings that catecholami...

The tick-transmitted Babesia and Theileria spp. parasites are detrimental for animal health and cattle production in vast tropical and subtropical areas of the world. Additionally, human babesiosis increasingly raises public health concern. Most of the research on these piroplasmids has been focused on mammal-infecting stages, while the interaction with their tick vectors has been widely neglec...

This article explores structural-strategic family therapy as a treatment modality for couples with problems of intimacy and sexual desire. Parents whose presenting problem involves a child with problematic behavior may also struggle with problems in their intimate relationship. Instead of speaking to these problems directly, however, the couple may communicate about their intimate problems via ...

Although attachment security is relatively stable over time, individuals do experience significant within-person variation in their attachment security across time. No research to date, however, has assessed the relational consequences of within-person variation (fluctuations) in attachment security toward a specific attachment figure. Study 1 (N 409) first examined whether attachment security ...

To determine the prevalence and determinants of intimate partner violence, 2400 married women attending public clinics in Babol, Islamic Republic of Iran, were screened for domestic violence. Overall, 15.0% of women had suffered physical abuse from their husbands in the previous year, 42.4% sexual abuse and 81.5% various degrees of psychological abuse. A significant association with intimate pa...

Ethnic differences and commonalities rarely have been the focus of community-based research on violence against women. The few existing studies typically used survey instruments developed on and used with Anglos and simply applied them to members of other ethnic groups. The proposed conceptual framework is based on a review of the published literature and on information gleaned from focus group...

The purpose of this study was to identify predictors of risky alcohol use and alcohol-related consequences among postdeployment soldiers. Demobilizing soldiers completed an assessment packet that included questions about demographic factors, relationships, stress, and alcohol-related consequences. Significant predictors of greater alcohol-related consequences, as assessed with the CAGE question...

OBJECTIVE This study explored the main and interactive effects of sexual abuse history and relationship satisfaction on self-reported parenting, controlling for histories of physical abuse and parental alcoholism. METHOD The community sample consisted of 90 mothers of 5- to 8-year-old children. The sample was limited to those mothers currently in an intimate relationship, 19 of whom reported ...

Resident microorganisms, known as the microbiota, are essential for many physiological functions including protection against pathogens. Microbiota is indeed required proper immune system development and function, can also host-independently protect infections. Thus, a co-constructed view of host involving both named “co-immunity,” has been proposed, idea an “immunological holobiont” suggested....