Objective The aim of this work is to evaluate the safety and efficacy repeated sessions modified corneal collagen cross linking (M-CXL) combined with intrastromal injection voriconazole for treatment severe fungal keratitis ongoing melting compare outcome alone. Patients Methods This a retrospective comparative clinical cohort study. Thirty eyes clinically suspected lab-confirmed were included....

A 30 year old female presented with a large post traumatic iris cyst obstructing the visual axis, with a corneal scar inferiorly. Anterior segment optical coherence tomography (AS-OCT) was done to identify the areas of corneal attachment and locate the thinnest area of the cyst. Nd:YAG laser iridocystotomy performed subsequently resulted in immediate deflation of the cyst, excellent restoration...

PURPOSE Corneal tissue shortage has become a major concern worldwide, which has motivated the search for alternative solutions to eye bank human eyes for corneal transplantation. Minimally invasive lamellar transplantation and tissue engineering may offer new opportunities for the rehabilitation of diseased corneas. The aim of this study was to evaluate the biocompatibility and functionality of...

An intrastromal injection of endotoxin lipopolysaccharide (LPS) in one eye of New Zealand albino rabbits induced a prominent keratitis characterized clinically and microscopically by edema and infiltration. Polymorphonuclear leukocytes (PMNs) constituted the primary invading leukocytic element. Collagen synthesis was measured by pulsing the corneas with 3H-proline before inducing inflammation. ...

High water content hydrogels can be made with water and solute permeabilities comparable to those of the corneal stroma, thus making them feasible as intrastromal implants for refractive keratoplasty. The materials have been shown to be compatible with the cornea tissue, but for a lenticule of hydrogel to be effective in a refractive keratoplasty procedure it must alter the anterior curvature o...

JUNE 2010 CATARACT & REFRACTIVE SURGERY TODAY EUROPE 23 A s we reported in the Journal of Cataract and Refractive Surgery,1 use of a thick intrastromal corneal ring segment (ICRS) may enhance the surgical effect in patients with keratoconus. Although commercially available ICRSs are limited in thickness, one can achieve the effect of thicker segments by stacking two within a single intrastromal...