Two methods for determining ranitidine hydrochloride (RNH) in pure drug and in formulations using potassium iodate and dichlorofuorescein are described. Titrimetry involves the oxidation of RNH by a known excess of potassium iodate in acidic conditions followed by iodometric determination of surplus iodate. In spectrophotometry also, the drug is oxidized by a large excess of iodate and the iodi...

Magnetic skyrmions, which are topologically distinct magnetic spin textures, gaining increased attention for their unique physical properties and potential applications in spintronic devices. Here we present a design strategy skyrmion host candidates based on combinations of spin, asymmetric building units having stereoactive lone-pair electrons, polar lattice symmetry. To demonstrate the viabi...

Introduction Iodine is an essential nutrient found in seawater, seafood, and iodine-enriched food, such as iodized table salt. The most common forms of iodine in diet are iodide and iodate, with additional iodo-organic compounds providing a small fraction of bioavailable iodine. Iodine deficiency affects thyroid hormone production and leads to developmental diseases, goiter, and paralysis.1 Tab...

A new method for colorimetric determination of urinary hydroxylysine is described. Approximately one-hundredth of human urine collected for 24 hr was diluted to 25 ml and titrated to pH 2.0 with 2 hcl, and then subjected to column chromatography on Dowex 50 X 4 (H+ form). Amino acids were eluted from the column with 1.5 N NH4OH. Hydroxylysine in the elute with 1.5 N NH4OH was separated from th...

Singlet oxygen production in the chloroperoxidase-hydrogen peroxide-halide system was studied using 1268 nm chemiluminescence. With chloride or bromide ions, singlet oxygen is produced by the mechanism (formula; see text) (formula; see text) where X- is chloride or bromide ion. Under conditions where there is high enzyme activity and when Reaction B is fast relative to Reaction A, singlet oxyge...

Sl ides pre p ared w i t h suspens ions o f My co ba c /eri!l m leprae recovered fro m s k i n b i o p s y s p e c i m e n s o b t a i n e d fro m t rea t e d l e p ro m a t o u s l e p ro s y p a t ie n ts a n d o x id i zed w i t h per iodate c o n t a i n e d on lhe ave rage 3 6% m o re ac id-fast b a c t e ri a ( A F B ) l h a n d i d d u p l i c a t e s l i d es s t a i n c d by t h e s t ...

The essentiality of iodine for humans, especially in the early stages of life, is well recognized. The chemical forms of iodine in food supplements, infant formulae and iodated salt are either iodide (KI) or iodate (KIO3). Because there are no or rare data about iodine uptake by yeasts, we investigated the influence of different sources of iodine, as KI, KIO3 and periodate (KIO4), on its uptake...

In the routine thyrotropin assay based upon the depletion of iodine in the chick thyroid gland following thyrotropin injections, a rapid micromethod for the determination of iodine was desirable. Elmer (1) gives an excellent critical review of the existing methods for iodine determination up to 1936. Kirk (2) reviews the present methods and techniques for microanalysis, including iodine. The me...

A polymer/mediator composite modified glassy carbon electrode (GCE) is fabricated for electrochemical detection of iodate (IO3 ). Flavin adenine dinucleotide (FAD) is chosen as mediator for sensing iodate, and 3,4 ethylenedioxythiophene (EDOT) is chosen for entrapping FAD and forming a conducting polymeric matrix, poly(3,4 ethylenedioxythiophene) (PEDOT). The PEDOT/FAD modification layer is ele...