OBJECTIVE It is recognized that diagnostic doses of (131)I larger than 3 mCi will cause some cell injury to the tissue in which it concentrates and reduce subsequent uptake of (131)I administered therapeutically. Iodine-123 has been suggested as an alternate radiopharmaceutical to perform whole-body scans since its primary emissions are photons with minimal particulate radiation and it does not...

OBJECTIVE To compare the cost-effectiveness of fine-needle aspiration biopsy, iodine 131 scintigraphy, and ultrasonography for the initial diagnostic workup of a solitary palpable thyroid nodule. DESIGN A deterministic cost-effectiveness analysis was conducted using a decision tree to model the diagnostic strategies. SETTING A single, mid-Atlantic academic medical center. MAIN OUTCOME MEA...

i131 is a famous radio-iodine isotope in use for diagnosis and treatment of hyper functioning and cancerous thyroid gland. it is a nuclear reactor product; however nuclear reactor may be unavailable in some areas. replacement by i-124 may be possible, another iodine isotope producible by cyclotron; a system more available than reactor. here absorbed fraction of gamma and beta rays of i-124 thro...

PURPOSE Immunotherapy using monoclonal antibodies to specifically target B cells has provided new hope to many patients with indolent lymphomas, particularly those with chemotherapy-refractory disease. Lymphomas are extremely sensitive to radiation, and significant progress has been made over the last decade in the development of radioimmunotherapy with anti-CD20 antibodies. MATERIALS AND MET...

BACKGROUND A cross-sectional prospective study has been conducted on differentiated thyroid cancer (DTC) patients using negative (131)Iodine ((131)I) whole body scans and elevated thyroglobulin (Tg) levels. The main objective of this research was to determine the prevalence of the conversion of differentiated to dedifferentiated thyroid cancer patients during follow up at the Hospital Kuala Lum...

Introduction: High-dose radioactive iodine therapy in differentiated thyroid cancer (DTC) may adversely affect the salivary gland function. This study is aimed to evaluate the effect of radioactive iodine (RAI) with dose of 100 mCi in DTC patients compared to lower doses of less than 30 mCi in hyperthyroid cases. Methods: Fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...

When the former method is employed for production, enriched uranium irradiated for 2-3 weeks in the nuclear reactor is dissoivoc! in nitric acid and the iodine-131 is distilled and collected. '*) But separation of iodine-1 31 from pile irradiated tellurium targets is the most commonly used method of production. The methods <d Reparation varies for different targets. With metal tellurium the tar...

Adjuvant therapy of differentiated thyroid cancer with radioactive iodine ((131)I) is a standard procedure for the ablation of remnant thyroid tissue following surgery and for the treatment of iodine-avid metastases. Presently, there are two dosimetric concepts for the treatment of thyroid cancer using radioiodine: a) the bone marrow dose limited approach and b) lesion-based dosimetry. Both con...

The results of this study has revealed a significant increase in I(131) uptake of cultivated thyroid gland in the media containing petroleum ether extract of Commiphora mukul. Besides, T(3) resin uptake, protein bound iodine as well as free thyroxine index in the media are also observed to be significantly (P 0.001) increased. When explants are cultivated in the media containing melatonin, ther...

RATIONALE Post-therapy or diagnostic whole-body radioiodine scintigraphy is widely employed to evaluate the residual, recurrence, or metastases of differentiated thyroid carcinoma because of the high sensitivity and accuracy. However, it has pitfalls. PATIENT CONCERNS We described a 63-year-old male with a history of papillary thyroid carcinoma who was referred for iodine-131 ablation therapy...