نتایج جستجو برای: iodobenzylguanidine

تعداد نتایج: 1080  

Journal: :Organic & biomolecular chemistry 2012
Hajime Abe Kotaro Okada Hiroki Makida Masahiko Inouye

Amphiphilic 2,6-pyridylene ethynylene "meta-ethynylpyridine" polymers having chiral oligo(oxyethylene) side chains were developed as hosts for saccharide recognition. The polymers were prepared via a Sonogashira reaction and fractionated by gel permeation chromatography (GPC). They showed circular dichroism (CD) activity due to their higher-order chiral helical structures, and their CD and UV-v...

2017
Hannes P L Gemoets Gabriele Laudadio Kirsten Verstraete Volker Hessel Timothy Noël

Described herein is an effective and practical modular flow design for the meta-selective C-H arylation of anilines. The design consists of four continuous-flow modules (i.e., diaryliodonium salt synthesis, meta-selective C-H arylation, inline copper extraction, and aniline deprotection) which can be operated either individually or consecutively to provide direct access to meta-arylated aniline...

Journal: :The Journal of pharmacology and experimental therapeutics 2008
Lorraine Yau Peter Molnar Michael C Moon Shelly Buhay Jeffrey P Werner Katerina Molnar Laura Saward Dario Del Rizzo Peter Zahradka

The association of ADP-ribosylation with cell proliferation and ischemia-reperfusion injury suggests that it may be a suitable target for therapeutic control of revascularization-induced injury. The purpose of this study was to investigate the inhibitory actions of ADP-ribosylation inhibitors on restenosis. In organ culture, the poly(ADP-ribose) polymerase (PARP) inhibitor 3,4-dihydro-5-methyli...

Journal: :Cancer research 1989
L A Smets C Loesberg M Janssen E A Metwally R Huiskamp

Radio-iodinated m-iodobenzylguanidine (MIBG), an analogue of the neurotransmitter norepinephrine (NE), is increasingly used in the diagnosis and treatment of neural crest tumors. Active uptake and subsequent retention of MIBG and NE was studied in human neuroblastoma SK-N-SH cells. Neuron-specific uptake of [125I]MIBG and [3H]NE saturated at extracellular concentration of 10(-6) M and exceeded ...

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