Canthaxanthin is a carotenoid that lacks pro-vitamin A activity but is known to have antioxidant activity. The products of its oxidation in oxygen were found to be mainly substituted apo-carotenals and apo-carotenones. The product profile resembles that obtained in the oxidation of β-carotene, except that with canthaxanthin these products are the 4-oxo-β-apo-carotenals and 4-oxo-β-apo-carotenon...

some oxime ether derivatives of α-ionone (4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-one) have been synthesized. reaction of 4-(2,6,6-trimethyl-2-cyclohexen-1-yl)-3-buten-2-ketoxime with various chloro and fluoro aromatic and hetero aromatic compounds gave the corresponding oxime ether derivatives via aromatic nucleophilic substitution (snar). the structures of these compounds were elucida...

Photoaffinity labeling with bovine rhodopsin using a retinal with a fixed 11-cis-ene cross-linked exclusively to Trp-265/Leu-266 in helix F, showing that the beta-ionone C-3 is close to helix F. Moreover, since these labeled amino acids are in the middle of helix F, while the Schiff-base linkage to Lys-296 at the other terminus of the chromophore is also in the middle of helix G, the chromophor...

1. Vitamin A is the generic term designating any compound with beta-ionone structure having qualitatively the biological activity of retinol. The recommended posology is 10 000 to 20 000 IU/kg bw in calves and adult cattle, 6 000 IU/kg bw in sheep and goats, 1 500 IU/kg bw in horses, 2 000 to 3 000 IU/kg bw in pigs, poultry and rabbits either by oral, intramuscular and subcutaneous routes. Vita...

Two mammalian hCYP26A expression systems have been used to analyze the metabolic products of CYP26A. Through the use of extensive HPLC, UV spectroscopy, and liquid chromatography/tandem mass spectrometry (LC-MS/MS) methodology, we have conclusively demonstrated that the complex mixture of products comprises 4-OH-all-trans-retinoic acid, 4-oxo-all-trans-retinoic acid, and 18-OH-all-trans-retinoi...

The chemical composition of the hips essential oils of 9 taxa of Rosa L. was analyzed and compared using the standardized analytical GC and GC/MS methods. The volatile hips oil compositions for these species are presented. All oil samples were dominated by following components: vitispiran (isomer), a-E-acaridial, dodecanoic acid, hexadecanoic acid, docosane (C22), beta-ionone, 6-methyl-5-hepten...

From the fresh leaves or twigs of Aptenia cordifolia, a total of 29 compounds were isolated, including the new tetranoroxyneolignan 18, the new dilignan 19, and the beta-ionone derivative 27, previously only known as a synthetic compound, together with 26 known compounds. The structures of the new products were determined by (1)H-, (13)C-, and 2D-NMR, as well as HR-MS analyses. The phytotoxic e...

Presently, functional foods and nutraceuticals are gaining immense importance in the prevention of various maladies through dietary regimen module. Consumption of fruits and vegetables based diet has pursuit a range of bioactive components, especially phytochemicals targeting life threatening ailments. In this context, lycopene is an extensively studied antioxidant potentially present in waterm...