BACKGROUND Polycystic ovary syndrome (PCOS) is associated with a range of challenging symptoms which impact patient's lives. Iranian women with PCOS are likely to face a number of unique difficulties given particular societal and cultural norms for women. Understanding health-related quality of life (HRQoL) from a patients'perspective is critical to developing the appropriate support interventi...

Tumor growth is characterized by uncontrolled cell division. For centuries, silver kushta powder, composed of nano and submicro silver particles, has been used in traditional Iranian and Pakistani medicine for the treatment of melanoma and breast cancer. We have found that these nanocomposite particles are similar to silver nanoparticles (AgNps) in size and shape and that there are so differenc...

BACKGROUND Currently, there are no effective vaccines against leishmaniasis, and treatment using pentavalent antimonial drugs is occasionally effective and often toxic for patients. The PTR1 enzyme, which causes antifolate drug resistance in Leishmania parasites encoded by gene pteridine reductase 1 (ptr1). Since Leishmania lacks pteridine and folate metabolism, it cannot synthesize the pteridi...

OBJECTIVE Despite the fact that the mobile phone has become a pervasive technology of our time, little research has been done on mobile dependency. Therefore, a valid and reliable instrument, conforming to Iranian culture seems essential. The aim of our study was to validate the Iranian version of MPPUS (Mobile Phone Problematic Use Scale). METHODS This was a cross-sectional research, in whic...

BACKGROUND The prevalence of vitamin D deficiency and its causative factors has been estimated more frequently in elder population, women, and patients with osteoporosis in different countries, but this issue is less defined in male population within different age groups especially in Asian countries. Therefore, we studied the role of effective factors in vitamin D deficiency and its prevalence...

Research suggests a relatively sizable rate of unintended pregnancies in some subgroups of Iranian women, but there is no concise, standard scale to measure the pregnancy intention of Iranian women. Therefore, the psychometric properties of the Persian version of the London Measure of Unplanned Pregnancy (LMUP) were investigated. The Persian version of the LMUP was tested on randomly selected m...

BACKGROUND Hepatitis B virus (HBV) is a serious risk factor for several severe liver diseases such as cirrhosis and hepatocellular carcinoma. HBV, like other viruses, uses several mechanisms to escape from specific immune responses including the use of mutations in the genome which lead to epitope variations. There are several immune responses, including T helper cells, cytotoxic T lymphocytes,...

BACKGROUND Researchers and academic institutions need assessment and rating to measure their performance. The criteria are designed to evaluate quality and adequacy of research and welcome by most universities as an international process to increase monitoring academic achievements. The study aimed to evaluate the increasing trend in global ranking of Iranian medical universities websites empha...

BACKGROUND Marital instability is affected by many factors. In Iran, socio-cultural and political limitations are obstacles for sexuality-related studies; therefore, insufficient in- formation is available in this area. In the present research, we investigated the relation- ship between marital instability and sexual satisfaction among Iranian women. MATERIALS AND METHODS A case-control study...

BACKGROUND Based on the authors' knowledge, there is no study on the co-infection of opportunistic agents such as Mycobacterium tuberculosis and Pneumocystis jirovecii in the lungs of Iranian patients with immunosuppression. OBJECTIVES The current study aimed to show the rate of co-infection of M. tuberculosis and P. jirovecii in patients with Human Immunodeficiency Virus (HIV). PATIENTS AN...