this study was done to determine whether high or low dose of anti-snake venom (asv) is better in coagulopathy in victims of envenoming by vipers. this retrospective study was conducted on the 154 patients (mean age ± sd, range) of viper snake bites who were referred to the emergency ward of razi hospital, ahvaz, iran over 2 years period (2004 - 2006). according to the treatment dosage the patie...

A kininogenin (EC 3.4.21.8) was purified from the venom of Vipera ammodytes ammodytes (European sand viper) by a combination of gel filtration and ion-exchange chromatography. The enzyme is approximately six times more active than bovine trypsin in its ability to release vasoactive peptides from a plasma precursor. The kininogenin is a glycoprotein containing 18-20% by weight of carbohydrate. I...

although some venoms and their isolated compounds have been shown to have antibacterial properties, most have not been investigated for such activity. echis carinatus is one of the most venomous snakes in the world and has an effective haematotoxic venom that destroys endothelial cells and causes haemorrhagia. in this study, the antibacterial activity of iranian snake echis carinatus venom agai...

This epidemiological review was carried out to display the magnitude and the geographic distribution of scorpion envenomation in Iran with focus on the southwestern region of Iran, particularly. The Iranian recognized scorpions belonging to two families, including Buthidae and Scorpionidae. Buthidae family consists of 14 genuses, 26 species, and 18 sub-species, while Scorpionidae family has thr...

Severe allergic reactions during specific immunotherapy may occur in the treatment of hymenoptera sting allergy. The objective of the present study was to examine the characteristics of allergic reactions during specific immunotherapy in patients with allergy towards hymenoptera venom in the Iranian population. A prospective study was performed using the clinical reports of 27 patients with ana...

BACKGROUND Scorpion venom is important and rich source of peptides, most of which have been widely used as pharmacological tools for unraveling structure-function relationship of various ion channels. Naturally occurring toxins can be also considered as lead compounds in the development of novel drugs. OBJECTIVES In this context, the scorpion-derived peptide neurotoxins specific to sodium cha...