AIM The purpose of this study was to describe the occurrence of self report bloating and related factors in patients with irritable bowel syndrome (IBS). BACKGROUND Bloating symptoms are common in patients with IBS and have significant impact on normal daily function. PATIENTS AND METHODS This study was a community-based cross-sectional survey that conducted using a valid questionnaire base...

INTRODUCTION Resilience and Psychological Wellbeing are two important concepts in adaption of patients to chronic disease conditions. GOAL To compare resilience and psychological wellbeing in women with irritable bowel syndrome and normal women. METHODS This was an analytical-comparative study. The statistical population consisted of all patients with irritable bowel syndrome visiting Imam ...

AIM To identify simple, objective, accurate histological criteria for distinguishing acute infective-type colitis, chronic idiopathic inflammatory bowel disease, and irritable bowel syndrome on rectal biopsy in patients with acute onset diarrhoea at first presentation, one to 10 weeks after onset. METHODS Cell counts and measurements of mucosal architecture were made on initial rectal biopsie...

BACKGROUND AND AIMS Inflammation may play a role in the pathogenesis of irritable bowel syndrome in some individuals, such as in those who develop symptoms following a dysenteric illness. Persisting inflammation, resulting from an imbalance of cytokines regulating the inflammatory response, is one possible mechanism. As the elaboration of cytokines is under genetic control, this study was desig...

OBJECTIVE To determine the effectiveness of increasing the dietary content of soluble fibre (psyllium) or insoluble fibre (bran) in patients with irritable bowel syndrome. DESIGN Randomised controlled trial. SETTING General practice. PARTICIPANTS 275 patients aged 18-65 years with irritable bowel syndrome. INTERVENTIONS 12 weeks of treatment with 10 g psyllium (n=85), 10 g bran (n=97), ...

Mycobacterium avium subsp. paratuberculosis causes Johne's disease, a systemic infection and chronic inflammation of the intestine that affects many species, including primates. Infection is widespread in livestock, and human populations are exposed. Johne's disease is associated with immune dysregulation, with involvement of the enteric nervous system overlapping with features of irritable bow...

Studies from the Western hemisphere have established the efficacy and safety of tegaserod in women with irritable bowel syndrome and constipation. This review summarizes the results of recent studies from around the world that confirm the efficacy and safety of tegaserod, and expand our understanding of the role of this drug in the treatment of patients with irritable bowel syndrome.

OBJECTIVES Revisions of the diagnostic criteria for irritable bowel syndrome have led to varying prevalence estimates. The Rome III criteria require a lower symptom frequency than Rome II (at least 10% of the time for Rome III, compared with at least 25% of the time for Rome II). In an epidemiological survey of a representative sample of Israeli adults using Rome II, we reported the prevalence ...

• To get a global understanding of the pathophysiology of irritable bowel syndrome, idiopathic chronic constipation, and diverticular disease for a more rational use of dietary tools in these conditions; • To learn about the true impact of “food intolerance” on symptoms of irritable bowel, thereby gaining insight into the role of excluding selected food from the diet of these patients; • To kno...