Long-term depressive behavior was modeled via immunization of white rats with isatin (an endogenous MAO inhibitor) covalently bound to a carrier antigen. The immunization of rats against isatin and several exogenous MAO inhibitors (pargyline and deprenyl) resulted in long-term (2 months) depressive-like behavior with elements of anxiety and an increased activity of MAO in the brain. In contrast...

In the title compound, C(14)H(10)FN(3)O, the six- and five-membered rings of the isatin moiety and the six-membered ring of phenyl-hydrazone are nearly planar with r.m.s. deviations of 0.0003, 0.0004 and 0.007 Å, respectively. The dihedral angle between the phenyl ring and the isatin ring system is 6.09 (9)°. The mol-ecular structure is stabilized by a strong intra-molecular N-H⋯O hydrogen bond...

In the title 1-alkyl-isatin 3-thio-semicarbazone, C(19)H(28)N(4)OS, the imine C=N bond has a Z configuration, whereas the N-N-C=S unit has an E conformation. In the crystal, mol-ecules are connected by N-H⋯O hydrogen bonds, forming zigzag chains running along the b axis.

INTRODUCTION A new method for preparation of silver nanoparticles (AgNPs) based on using hydrazino-isatin derivatives in an aqueous methanol reaction medium is reported here. AgNPs were prepared using silver nitrate solubilized in a water core as the source of silver ions and 3-hydrazino-isatin derivatives (3-hydrazino-isatin [IsH] and 1-benzyl-3-hydrazino-isatin [BIsH]) solubilized in methanol...

The current approach involves the kinetic investigation of Thiobenzamide (TB) and cyclohexanone thiosemicarbazone (CTSC) in solution with 3-chloroacetylacetone(3-CAA). study revealed a second-order rate constant respect to both reactants, thioamide an α-halo carbonyl compound. energy activation (Ea) was found be Ea 48.8176 kJ/mol/K for thiobenzamide 33.08692157 Cyclohexanone thiosemicarbazone. ...

isatin, n-methyl isatin and n-benzylisatin were smoothly monobrominated in the 5-position by treatment with pyridinium bromochromate (pbc) in acetic acid medium. in the similar conditions indigo underwent bromination and oxidation to give 5-bromoisatin in high yield.

In the title isatin compound, C(16)H(18)N(2)O(6), the pyrrolidine ring adopts an envelope conformation and is inclined at a dihedral angle of 7.31 (5)° with respect to the benzene ring. The acetyl group is disordered over two positions with refined occupancies of 0.503 (4) and 0.497 (4). These groups make dihedral angles of 12.6 (6) and 19.6 (7)° with the pyrrolidine ring. In the crystal struct...

Mixed ligand octahedral Titanium(III) complexes with the tridentate salicylaldehydesemi-, thiosemiand isothiosemicarbazone and pyridine of general formula [Ti(L)(py)3]X(H2L 1 = salicylaldehyde semicarbazone,X=[TiCl3(py)] -, ClO4 .H2O, I . 0.5 I2; H2L 2 = salicylaldehyde thiosemicarbazone, X = [TiCl3(py)] ,[Ti Br3(py)] -, ClO4 . H2O, I3 -; H2L 3 = salicylaldehyde Smethylisothiosemicarbazone,X = ...