Over the past 3 decades, several observational studies established a role for the left ventricular reconstruction procedure (LVR) in the treatment of ischemic cardiomyopathy. In 2009, the Surgical Treatment for Ischemic Heart Failure (STICH) trial reported their findings and found no benefit of adding LVR to coronary artery bypass surgery in ischemic dilated cardiomyopathy. The STICH findings p...

BACKGROUND Modulation of sympathetic tone may contribute to statin-mediated reduction in sudden cardiac death. We examined the effect of simvastatin on heart rate variability (HRV) in patients with non-ischemic dilated cardiomyopathy to evaluate for an antisympathetic effect of statins independent of anti-ischemic properties. METHODS The study was a prospective, open-label, self-controlled tr...

o a i “ l f o t i o Functional mitral regurgitation typically occurs in patients with ischemic cardiomyopathy or idiopathic dilated cardiomyopathy and is independently associated with excessive morbidity and mortality (1–8). In functional mitral regurgitation, it has been demonstrated that abnormal mitral valve kinematics result from a restriction of leaflet closure as a result of enhanced apic...

Peripartum cardiomyopathy (PPCM) is a rare form of dilated cardiomyopathy that is associated with high maternal morbidity and mortality. Onset is usually between the last month of pregnancy and up to the fifth month postpartum. PPCM usually presents with signs and symptoms of heart failure and rarely with thromboembolic complications. The true incidence of thromboemboli in PPCM is unknown. Here...

conclusions the hormonal levels were low in patients with idiopathic dilated cardiomyopathy. however, the prognostic significance of different hormonal deficiencies was not clear in our study populations who were receiving standard therapies for heart failure and had a relatively stable clinical condition. results except for testosterone level, the levels of gh, igf-1, t3, and t4 concentrations...

conclusions diagnosis of tachycardia-induced cardiomyopathy in children is important, since appropriate treatment improves the prognosis. every child with recurrent and persistent palpitation with the first episode of congestive heart failure should be evaluated for tachycardia- induced cardiomyopathy. introduction tachycardia-induced cardiomyopathy (tic) is a ventricular dysfunction secondary ...