Knowledge of the radiochemical purity of radiopharmaceuticals is mandatory and can be evaluated by several methods and techniques. Planar chromatography is the technique normally employed in nuclear medicine since it is simple, rapid and usually of low cost. There is no standard system for the chromatographic technique, but price, separation efficiency and short time for execution must be consi...

Metal powder injection molding is a shaping technology that has achieved solid scientific underpinnings. It is from this science base that recent progress has occurred in titanium powder injection molding. Much of the progress awaited development of the required particles with specific characteristics of particle size, particle shape, and purity. The production of titanium components by injecti...

While HPLC has traditionally been the method of choice for purity determination of pharmaceutical substances, capillary electrophoresis (CE) offers a different selectivity and hence it is a complementary technique to HPLC. Loratadine, an antihistamine, could include in its raw material seven impurities that ought to be separated, identified and quantified for drug development and quality contro...

Although a number of methods are available for evaluating Linezolid and its possible impurities, a common method for separation if its potential impurities, degradants and enantiomer in a single method with good efficiency remain unavailable. With the objective of developing an advanced method with shorter runtimes, a simple, precise, accurate stability-indicating LC method was developed for th...

Y2O3:Eu were prepared through precursors synthesized by leaching tests, removing impurities, enrichment of Y and Eu from residual purified liquors, annealing treatment, and high temperature solid-state reaction method, which is the most suitable for large-scale production. The analysis of product shows that the purity is 99.42%. The resultant powders were characterized by X-ray diffraction (XRD...

Understanding the pathophysiology of Alzheimer disease has relied upon the use of amyloid peptides from a variety of sources, but most predominantly synthetic peptides produced using t-butyloxycarbonyl (Boc) or 9-fluorenylmethoxycarbonyl (Fmoc) chemistry. These synthetic methods can lead to minor impurities which can have profound effects on the biological activity of amyloid peptides. Here we ...

Two HPLC methods such as cefadroxil and cefalexin methods were compared in their performance for the quantitative analysis of the content and purity of β-lactamic antibiotic, cefradine, for six bulk drug samples. Between the two methods, the cefadroxil method prescribed by the European Pharmacopoeia (EP) for the determination of impurities in cefradoxil was superior to the cefalexin method pres...

Chemical purification of Phenanthrene can be achieved by conventional laboratory techniques, such as preparative HPLC. However, this process presents several drawbacks: i) tendency of adding solvent impurities to the targeted compound; ii) limitations in the separation, especially with other fused ring compounds such as Anthracene, Fluorene, etc. By contrast, the zone melting technique [1] has ...

Because of its ability to produce silicon crystals of exceptionally high purity and crystallographic perfection, the float-zone method lends itself to use as a tool for the controlled study of deliberately introduced defects and impurities in Si crystals and their effects on materials properties such as minority charge-carrier lifetime or photovoltaic conversion efficiency. Some examples of suc...

The electric, electronic, mechanical and thermal characteristics of high density electronic devices can be affected by the physico-chemical characteristics of base materials as well as by trace impurities. It is well known that soft errors caused by trace -emitting impurities are one cause of the faulty operation of electronic devices. This phenomenon was initially reported in May[1] in the 197...