Objectives: The term, ‘varicose veins’ is used commonly to describe the enlargement and tortuosity of lower extremity veins. However varicose veins can occur elsewhere. The traditional surgical treatment has been vein stripping to remove the affected veins. In this article we aimed to present common anatomical variations of saphenofemoral junction encountered during surgical procedures in young...

Mouse livers were perfused in situ through the portal vein with the disaccharides sucrose, lactose, maltose, and cellobiose in hypertonic concentrations (0.5 M). This treatment resulted in plasmolysis of the hepatocytes and splitting of the gap junctions and zonulae occludentes. The junctions split symmetrically, leaving a half-junction on each of the two separated cells. The process of junctio...

In contrast to thoracolumbar dural arteriovenous fistulas (DAVFs), the clinical features of craniovertebral junction (CVJ) DAVFs are not fully known presumably because of a pausity of data. Three cases of CVJ DAVF were reported here and a review of the literature was made to clarify their clinical features and treatment strategies. Thirty one patients with CVJ DAVFs including ours were collecte...

BACKGROUND Open dismembered pyeloplasty remains the preferred surgical technique for ureteropelvic junction syndrome (UPJS) in most paediatric urology units. The authors present their experience of 230 patients and describe their form of presentation, treatment and early and long-term results. MATERIALS AND METHODS Retrospective analysis of clinical records of 230 patients submitted to dismem...

Clinical practice guidelines have been developed after multi-disciplinary consensus based on best available literature. As the name suggests, these are to be used as a guide only. These guidelines do not replace physician judgment which is based on multiple factors including, but not limited to, the clinical and social scenario, comorbidities, performance status, age, available resources and fu...

INTRODUCTION Laparoscopic pyeloplasty was first described by Schuessler. During the last decade, this technique has been developed in order to achieve the same results as open surgery, with lower rates of morbidity and complications. In this study we review our experience using laparoscopic pyeloplasty as the gold standard for the treatment of the ureteropelvic junction obstruction (UPJO). MA...

Pyeloplasty remains the gold standard therapy in the treatment of ureteropelvic junction obstruction. Laparoscopic pyeloplasty provides a minimally invasive alternative to open pyeloplasty without compromise of treatment success or durability. Presented is the surgical technique of laparoscopic pyeloplasty.

The functional characteristics of the tight junction protein ZO-3 were explored through exogenous expression of mutant protein constructs in MDCK cells. Expression of the amino-terminal, PSD95/dlg/ZO-1 domain-containing half of the molecule (NZO-3) delayed the assembly of both tight and adherens junctions induced by calcium switch treatment or brief exposure to the actin-disrupting drug cytocha...