Ionotropic glutamate receptor (iGluR) subunits contain a large N-terminal domain (NTD) that precedes the agonist-binding domain (ABD) and participates in subunit oligomerization. In NMDA receptors (NMDARs), the NTDs of NR2A and NR2B subunits also form binding sites for the endogenous inhibitor Zn(2+) ion. Although these allosteric sites have been characterized in detail, the molecular mechanism...

We propose a crash safe and pseudo-stabilizing algorithm for implementing an atomic memory abstraction in a message passing system. Our algorithm is particularly appealing for multi-core architectures where both processors and memory contents (including stale messages in transit) are prone to errors and faults. Our algorithm extends the classical fault-tolerant implementation of atomic memory t...

The homeotic Abdominal-B (Abd-B) gene expression depends on a modular cis-regulatory region divided into discrete functional domains (iab) that control the expression of the gene in a particular segment of the fly. These domains contain regulatory elements implicated in both initiation and maintenance of homeotic gene expression and elements that separate the different domains. In this paper we...

1. Shah SZA, Karam JA, Zeb A, et al. Movement is improvement: The therapeutic effects of exercise and general physical activity on glycemic control in patients with type 2 diabetes mellitus: A systematic review meta-analysis randomized controlled trials. Diabetes Therapy. 2021;12:707–732. https://doi.org/10.1007/s13300.... CrossRef Google Scholar

STUDY DESIGN In a human cadaveric burst fracture model with and without longitudinal ligament damage, the amount of anterior and posterior bone displacement (ABD, PBD) during balloon vertebroplasty after pedicle-screw instrumentation was investigated quantitatively. OBJECTIVES To investigate, in a burst fracture model with and without longitudinal ligament damage, the amount of ABD, PBD, and ...

1945 sonrasında Keynesçi anlayışla kurulan ve refah devleti politikaları çerçevesinde oluşturulan kapitalist yapının 1960'ların sonu itibariyle sorunlar yaşamaya başlaması, ABD İngiltere’de politikaların sorgulanmasını gündeme getirerek, yeni bir ekonomik modelin ikamesiyle sonuçlanmıştır. Bu bağlamda, Batı Avrupa’da komünist SSCB’nin etkisi dışında kalan birçok ülkede neoliberal ekonomi diye t...

An overview of the results of the Australian Burden of Disease (ABD) study is presented. The ABD study was the first to use methodology developed for the Global Burden of Disease study to measure the burden of disease and injury in a developed country. In 1996, mental disorders were the main causes of disability burden, responsible for nearly 30% of total years of life lost to disability (YLD),...

The genera Sinella and Coecobrya are reported from New Caledonia for the first time, with four new species: Sinella quadriseta sp. nov., S. claviseta sp. nov., S. copiosa sp. nov., and Coecobrya neocaledonica sp. nov. Sinella species studied here exhibit several morphological features that are not found in other non-cave species of the genus: paired teeth on inner edge of unguis closer to the b...

Thalassaphorura is the most diverse genus in China so far. Three new species (T. guangdongensis sp. nov., T. xihuensis sp. nov. and T. linzhiensis sp. nov.) are reported from China. T. guangdongensis sp. nov. is characterized by its pso formulae (32/122/33343 dorsally and 11/000/01010 ventrally), 4+4 medial p-chaetae between posterior pso on head, 2+2 chaetae on Abd. I-III terga along axial lin...