OBJECTIVES Kawasaki disease (KD) is an acute pediatric vasculitis of infants and young children with unknown etiology and no specific laboratory-based test to identify. A specific molecular diagnostic test is urgently needed to support the clinical decision of proper medical intervention, preventing subsequent complications of coronary artery aneurysms. We used a simple and low-cost colorimetri...

The biosynthesis, processing, and ligand-binding function of the membrane-associated and soluble forms of the folate-binding protein (FBP) in KB cells, a cultured human cell line, were studied using pulse-chase labeling with [35S] methionine. The intermediary and mature forms of the protein were isolated by immunoprecipitation and affinity chromatography and analyzed by sodium dodecyl sulfate e...

Abstract Background Kawasaki disease is a rare multisystem inflammatory condition that mainly affects children under the age of 5 years. Current theory pathogenesis an infectious stimulus triggers autoimmune reaction in genetically susceptible child. Recent studies demonstrated association with autoantibody response to EDIL3 (also known as DEL-1) KD. extracellular matrix protein which expressed...

A male child born of related parents suffered recurrent infections because of neutrophil actin dysfunction with increased amounts of a 47-kD protein and decreased amounts of an 89-kD protein (NAD 47/89). The patient and family members were studied to define the nature of the abnormal proteins and to examine their role in the functional defects of neutrophil actin dysfunction (NAD) 47/89 polymor...

Sera from 10 women with Chlamydia trachomatis culture positive cervicitis and sera from six men with C trachomatis positive non-gonococcal urethritis were studied for the presence of IgG, IgM, and IgA antibodies to polypeptides of C trachomatis elementary bodies and reticulate bodies using immunoblotting techniques. All the sera with IgG, IgM, or IgA immunoglobulins specific to C trachomatis re...

This study aimed to propose a method for the estimation of Secchi disk depth ( Zsd) values in northern Persian Gulf, Strait Hormuz, and Gulf Oman (N-PG-SH-GO), based on MODIS-Kd(490) data. The field-observed Zsd were collected during seven research cruises conducted by vessel between 2018 2021. A total number 114 observed 68 stations. daily Kd(490) MODIS-Aqua/L2 data downloaded all days (± thre...

Krabbe disease (KD) is a progressive and devasting neurological disorder that leads to the toxic accumulation of psychosine in white matter central nervous system (CNS). The condition inherited via biallelic, loss-of-function mutations galactosylceramidase (GALC) gene. To rescue GALC gene function CNS twitcher mouse model KD, an adeno-associated virus serotype 1 vector expressing murine under c...

Knowledge distillation (KD) is widely applied in the training of efficient neural network. A compact model, which trained to mimic representation a cumbersome model for same task, generally obtains better performance compared with being ground truth label. Previous KD-based works mainly focus on two aspects: (1) designing various feature knowledge transfer; (2) introducing different mechanism s...