To evaluate the efficacy of amniotic membrane in the management of painful bullous keratopathy secondary to the intractable glaucoma and in preventing exposure of drainage devices, we inserted Ahmed valve with amniotic membrane patch graft over the implant itself, and debrided corneal epithelium with amniotic membrane graft over the exposed stroma as a single operation. During the follow-up per...

PURPOSE One difficulty with Descemet's stripping automated endothelial keratoplasty (DSAEK) is air management during surgery and donor endothelial lamella centering. We evaluated the no-touch technique for donor centering and the use of a newly developed DSAEK donor adjuster. METHODS We evaluated the records of 12 consecutive patients (mean age 75.3 years) with bullous keratopathy who had und...

BACKGROUND AND OBJECTIVE To analyze the rationale for performing penetrating keratoplasty (PK) rather than Descemet's stripping automated endothelial keratoplasty (DSAEK) in patients with bullous keratopathy (BK) in Japan. PATIENTS AND METHODS A total of 136 eyes of 130 patients with consecutive BK were enrolled. Patients treated by DSAEK were categorized as the DSAEK group. The remaining pat...

Endothelial keratoplasty (EK) is the most exciting recent development in corneal transplantation. It has experienced surprisingly rapid growth in a very short period of time. One of the indications for EK is pseudophakic bullous keratopathy. However, concomitant intraocular lens (IOL) exchange, if indicated, may prove challenging. Some surgeons routinely perform IOL exchange with a scleral-fixa...

THE CONCEPT OF CXL In 1998, the proof-of-principle for corneal collagen cross-linking (CXL) was born from such a “simple” concept. Combining ultraviolet-A light and a chromophore (vitamin B2, riboflavin), the cornea could be stiffened within a mere half hour and progressive thinning diseases such as keratoconus could be halted.1,2 Although still considered a relatively new concept, CXL is now i...

purpose : to review current knowledge about ocular effects of sulfur mustard (sm) and the associated histopathologic findings and clinical manifestations methods : literature review of medical articles (human and animal studies) was accomplished using pubmed, scopus and isi databases. a total of 274 relevant articles in english were retrieved and reviewed thoroughly. results : eyes are the most...

purpose: to determine the indications for and surgical techniques of corneal transplantation at labbafinejad medical center (lmc) from 2004 to 2007. methods: in this descriptive study, records of 756 patients who had undergone corneal transplantation from october 2004 to october 2007 were reviewed. results: overall, 504 male (64.9%) and 272 female (35.1%) subjects with mean age of 41.29±21.25 (...

Corneal nerves are mainly derived from the ophthalmic branch of the trigeminal ganglion (TG). Corneal neuropathy contributes to epithelial degenerative changes in diabetic keratopathy. Efficient drug delivery to TG may be beneficial for the treatment of diabetic keratopathy. This article described intranasal delivery of nanomicelle curcumin to correct pathophysiological conditions in TG to prom...

PURPOSE To determine whether the incidence of and susceptibility to climatic droplet keratopathy (CDK), an acquired, often bilateral degenerative corneal disease, is influenced by the genetic background of the individuals who exhibit the disorder. METHODS To determine whether the disease expression was influenced by the genetic ancestry of CDK cases in native Mapuche of the northwest area of ...

PURPOSE To analyze endothelial cell density (ECD) decay after Descemet's stripping automated endothelial keratoplasty (DSAEK) and top hat keratoplasty (THPK) in patients with Fuchs' endothelial dystrophy (FED) and/or pseudophakic bullous keratopathy (PPBK). METHODS Patients underwent either THPK (n = 33) or DSAEK (n = 39) at the Erasmus Medical Center, Rotterdam. For each nonrandomized cohort...