Purpose: Promoter hypermethylation is an important mechanism of inactivation of tumor suppressor genes in cancer cells. Kidney tumors are heterogeneous in their histology, genetics, and clinical behavior. To gain insight into the role of epigenetic silencing of tumor suppressor and cancer genes in kidney tumorigenesis, we determined a hypermethylation profile of kidney cancer. Experimental Desi...

November 2006 In This Issue ● Bread and Kidney Cancer ● Nursing and CAM ● Occlusion Therapy for Lazy Eye in Children ● Joint Library Conference ● Aromatherapy and Recreational Diving ● CAM for Radiation Therapy ● NBScience International Conference of Biomedical Sciences ● Inside Natural Standard Natural Standard provides high quality, evidence-based information about complementary and alternati...

Clinical and experimental findings suggest that female hormonal and reproductive factors could influence kidney cancer development. To evaluate this association, we conducted analyses in 2 large prospective cohorts (the National Institutes of Health-AARP Diet and Health Study (NIH-AARP), 1995-2006, and the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO), 1993-2010). Cohort-...

PURPOSE Promoter hypermethylation is an important mechanism of inactivation of tumor suppressor genes in cancer cells. Kidney tumors are heterogeneous in their histology, genetics, and clinical behavior. To gain insight into the role of epigenetic silencing of tumor suppressor and cancer genes in kidney tumorigenesis, we determined a hypermethylation profile of kidney cancer. EXPERIMENTAL DES...

Metastatic tumors of the oral cavity are rare in occurrence. Renal cell carcinoma (RCC) metastasizes to organs head and neck 12–16% cases. RCC metastases tongue uncommon. A total 63 cases kidney cancer metastasizing have been reported literature. We report a clinical case metastasis skin lower eyelid (as initial manifestation disease) (11 months after diagnosis) one patient with metastatic canc...

Some tumors are known to have a definite cause-effect etiology, but renal cell carcinoma (RCC) is not one of them precisely. With regard to RCC we can only try to identify some clinical and occupational factors as well as substances related to tumorigenesis. Smoking, chemical carcinogens like asbestos or organic solvents are some of these factors that increase the risk of the RCC. Viral infecti...

The aim of the present study was to determine the expression and function of B cell translocation gene 1 (BTG1) in kidney carcinoma. Kidney samples were obtained from cancer lesions (n=85) and the adjacent normal tissue (n=40) in kidney cancer patients immediately following endoscopic biopsy. The effect of BTG1 overexpression was examined in vitro utilizing a human kidney cancer cell line, ACHN...

Malignant tumors of the kidney account for about 1.9% of total world cancers, with about 150,000 new cases annually. Renal parenchyma (renal cell) cancer represents around 80% of this total and nearly all of these cases are adenocarcinomas. As a whole, it is difficult to obtain clear descriptive patterns of incidence and mortality from renal cell cancer, since population data from different reg...

Chronic kidney disease (CKD) represents the fastest growing pathology worldwide with a prevalence of >10% in many countries. In addition, kidney cancer represents 5% of all new diagnosed cancers. As currently no effective therapies exist to restore kidney function after CKD- as well as cancer-induced renal damage, it is important to elucidate new regulators of kidney development and disease as ...

Approximately 1,700 cases of renal transplantation are performed annually, and various diseases may occur due to long-term internal use postoperative immunosuppressants. We experienced a case cervical cancer, which is thought be human papillomavirus (HPV)-related after living kidney transplantation, underwent laparoscopic radical hysterectomy.