Patients with spinal cord injury, subcortical stroke, neuromuscular diseases (including amyotrophic lateral sclerosis), and limb amputation have at least two characteristics in common: a brain that wants to direct movement and a body that fails to respond accordingly. Despite intact cortical function , central motor commands in persons with these paralyzing disorders are " disconnected " from t...

We report adaptive optics Hand K-band spectroscopy of the inner few arc-seconds of the luminous merger/ULIRG/QSO Mkn 231, at spatial resolutions as small as 0.085 ′′. For the first time we have been able to resolve the active star forming region close to the AGN using stellar absorption features, finding that its luminosity profile is well represented by an exponential function with a disk scal...

Correspondence to: Prof. Brunello Wüthrich, Allergy Unit, Department of Dermatology, University Hospital Zurich, Gloriastrasse 31 CH–8091 Zurich (Switzerland) Dear Sir, We read with interest the letter by Yamada et al. [1]. Our experience is in contrast with the results of the Japanese colleagues. In fact, we have published in the January 1994 issue of Allergy [2] that the measurement of solubl...

Kinetochores attach chromosomes to the mitotic spindle. After binding initially to the sides of spindle microtubules, they form stable attachments to microtubule plus ends so that chromosomes can be segregated to the spindle poles during anaphase. In addition , kinetochores recruit the spindle assembly checkpoint proteins that prevent cells from entering anaphase if their chromosomes aren't att...

A dipose tissue can release a plethora of factors termed adipokines. The large family of adipokines includes chemokines, cytokines, lipid factors, and growth factors. Adiponectin, the first cloned protein hormone from adipose tissue, is a metabolically active and anti-inflammatory adipo-kine. Adiponectin mainly circulates in different oligomeric isoforms, including high molecular weight adipone...

The asymmetry distributions for several kinematic variables are considered for finding a systematic way to maximize the signal for the extraction of the polarized gluon density. The relevance of mass effects for the corresponding dijet cross section is discussed and the different approximations for including mass effects are compared. We also compare via the programs Pepsi and Mepjet two differ...

is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain.specific expression of the murine surfactant protein A (SPA) gene is mediated by interactions between the SPA promoter and thyroid transcription factor-1. surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indi¬ cating common f...

A bstract. Signal processing in the immune syst em is st udied in a t heoretical multilayered network. The elements in th e network have regular conn ectiviti es, with t he level of connectivity reflecti ng t he level of signal (cyto kine) multifunctionality. Each element opera tes by th e same nonlinear majority rule. An exact formul a for t he/ {;umber of fixed points is derived as a fun ctio...

The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. A measurement of the ratio of the W and Z cross sections with exactly one associated jet in pp collisions at √ s = 7 TeV with ATLAS ✩ .ATLAS Collaboration a r t i c l e i n f o a b s t r a c t The ratio of production cross sections of the W and Z bosons with exactly one associa...

D uring mitosis, it's up to the kine-tochores assembled on the cen-tromeres of each chromosome to give a cell the go-ahead to begin anaphase. A kinetochore will only give its ready signal once it becomes attached to and stretched apart by microtubules emanating from both opposing spindle poles. This process, known as the spindle checkpoint , ensures the even distribution of chromosomes between ...