Certain chromosome rearrangements display a significant delay in replication timing that is associated with a delay in mitotic chromosome condensation. Chromosomes with delay in replication timing/delay in mitotic chromosome condensation participate in frequent secondary rearrangements, indicating that cells with delay in replication timing/delay in mitotic chromosome condensation display chrom...

A-kinase (or PKA)-anchoring protein AKAP95 is a zinc-finger protein implicated in mitotic chromosome condensation by acting as a targeting molecule for the condensin complex. We have identified determinants of chromatin-binding, condensin-targeting and chromosome-condensation activities of AKAP95. Binding of AKAP95 to chromatin is conferred by residues 387-450 and requires zinc finger ZF1. Resi...

Metastable triplet helium is an interesting atom, next to the alkalis and atomic hydrogen, to pursue Bose–Einstein condensation. In this paper an overview of the relevant physics of triplet helium and experimental progress in Amsterdam towards reaching Bose– Einstein condensation is described.  2001 Académie des sciences/Éditions scientifiques et médicales Elsevier SAS cold atoms / metastable ...

Water vapor condensation is commonly observed in nature and routinely used as an effective means of transferring heat with dropwise condensation on nonwetting surfaces exhibiting heat transfer improvement compared to filmwise condensation on wetting surfaces. However, state-of-the-art techniques to promote dropwise condensation rely on functional hydrophobic coatings that either have challenges...

There was a widespread belief among historians of science my generation that high competence with regard to content and languages alone can guarantee better, more reliable results than good philology combined in history or the other human sciences. In casestudy Wilbur R. Knorr’s analysis several medieval Arabic Latin texts on balance, steelyard, I highlight variety factors compromised time agai...

This paper extends the concept of 'epistemic object' by analyzing how knowledge-intensive design work is achieved in practice. We use ethnographic fieldwork to explore the case of architectural design in which epistemic 'objects' are constituted by visual representations. In the design projects that we observe, a wide range of knowledge forms need to be developed and aligned. We describe these ...