OBJECTIVE To optimize melanocyte/keratinocyte co-cultivation and to evaluate the effectiveness of autologous cultured epidermal grafts in the surgical treatment of stable vitiligo. DESIGN After optimization of melanocyte/keratinocyte cultures, achromic lesions were disepithelialized by means of programmed diathermosurgery (Timedsurgery) and covered with autologous epidermal grafts prepared fr...

BACKGROUND In vitiligo, melanocytes are gradually lost in depigmented macules of the skin. The disappearance of melanocytes has, however, not been clearly observed and consequently the aetiology of the disease (autoimmune, neural, cytotoxic) is still elusive. The starting point of vitiligo macules is frequently determined by local conditions such as wounds and excoriations, but may also follow ...

BACKGROUND Reactive perforating collagenosis (RPC) is a rare form of transepithelial elimination, in which altered collagen is extruded through the epidermis. There are 2 types of RPC, acquired RPC (ARPC) and inherited RPC, while the latter is extremely rare. Here we report on 1 case of ARPC. METHODS A 73-year-old female was presented with strongly itchy papules over her back and lower limbs ...

Background: Lichen Planus (LP) is a unique, common inflammatory disorder that affects the skin, mucous membrane, nail and hair. Though lichen planus has distinct colour, morphology and distribution it can present with variability. Objective: To know the incidence, various clinical manifestations, and correlation with histopathological findings. Methods: A total of 50 Lichen planus patients atte...

A 63-year-old Kenyan Asian man began haemodialysis involvement, the risk of secondary infection leading to either line sepsis or peritonitis, and the difficulties in in April 1997. He initially presented in 1988 dialysis dependent with an ANCA-associated systemic vasculperforming surgical procedures through involved skin. Koebner’s phenomenon (the recurrence of skin lesions itis, and was treate...