Severe infections due to Candida species have become more frequent during the past two decades because of the increasing numbers of immunosuppressed patients being treated in our hospitals. Distinguishing colonization from invasive disease requires knowledge of the pathogenetic mechanisms leading to invasion. To assist the clinician in therapeutic decisions, clinical microbiologists should iden...

Haemophilia is the only recognized haemorrhagic diathesis which is inherited as a sex linked recessive character. It is a disease of males which is transmitted through apparently unaffected females. The classical case can be recognized with certainty since the laboratory manifestations are specific. The association of a prolonged coagulation time with a normal bleeding time and platelet count, ...