Five clinically healthy calves received an intravenous injection of 25 g sodium D-lactate (223 mmol) in 100 ml sterile water and five control calves were given the same volume of 0.9 per cent sodium chloride. Two clinical examiners who were blinded to the status (test or control) of the calves observed that between eight and 40 minutes after the injections the calves that had received sodium-D-...

Lactate production in skeletal muscle has now been studied for nearly two centuries and still its production and functional role at rest and during muscle contraction is a subject of debate. Historically, skeletal muscle was seen mainly as the site of lactate production during contraction and lactate production associated with a lack of muscle oxygenation and fatigue. Later, it was recognized t...

Objective To evaluate whether a secondary increase of serum lactate levels in asphyxiated newborns during hypothermia treatment may reflect suboptimal dynamics. Methods-Retrospective case series and review of the literature. We present the clinical course of four asphyxiated newborns treated with hypothermia who presented with hypotension requiring inotropic support, and who displayed a seconda...

tracheomegaly or tracheobronchomegaly is a rare syndrome which is characterized by dramatic dilatation of the trachea and the major bronchi. this syndorme is usually associated with chronic respiratory infection and airway obstruction. in this paper, a case with tracheomegaly and bronchiectasis was scrutinized.

Assessment of disease severity in patients with septic shock (SS) is crucial determining optimal level care. In both pre- and in-hospital settings, blood lactate measurement broadly used combination the clinical evaluation as picture alone not sufficient for assessing outcomes. From 15th April 2017 to 2019, SS requiring prehospital mobile Intensive Care Unit intervention (mICU) were prospective...

To non-anaesthetized rats starved for 3 days, [U-14C]acetone, NaH14CO3, L-[U-14C]lactate, [2-14C]acetate or D-[U-14C]- plus D-[3-3H]-glucose was injected intravenously. From the change in the plasma concentration of labelled acetone versus time after the injection, the metabolic clearance rate of acetone was calculated as 2.25 ml/min per kg body wt., and its rate of turnover as 0.74 mumol/min p...