Shiga toxin-producing Escherichia coli (STEC) strains are food-borne pathogens that cause human diseases, and ruminants are usually important reservoirs of STEC. The first step of enteric infection is colonization of the host’s gut mucosal surface by pathogenic strains of bacteria. Probiotic bacteria can decrease the severity of infection by competing for receptors and nutrients and by synthesi...

This study investigates the possible synergistic stimulatory effects of prebiotic chitooligosaccharide and some commercial prebiotics on probiotic growth. Different combination with inulin, fructooligosaccharide, lactulose were prepared their ability to stimulate growth strains was evaluated. Following Chou-Talalay method, index calculated used for assessment. The data showed that most combinat...

Bu çalışmada, Kefir üretiminde farklı Lactobacillus (Lactobacillus delbrueckii ssp. bulgaricus ATCC 11842, helveticus 15009 ve plantarum 14917) ilave kültür kullanımının ACE inhibisyon aktivitesi patojenik bakterilere karşı antimikrobiyal aktivite gibi biyoaktif özellikleri üzerine etkisi araştırılmış proteoliz (HPLC peptit profilleri, HPLC serbest amino asit profilleri) incelenmiştir. Antimikr...

In this study, thiol/disulfide homeostasis in the liver tissues of high-fructose-fed rats was investigated conjunction with changes main hepatic detoxification enzyme, glutathione S-transferase (GST). Additionally, effects well-known probiotics namely Kefir, Lactobacillus helveticus, and plantarum supplementation on thiol/disulfate contents GST activity gene expression levels were analyzed. Fru...

We recently reported that Lactobacillus helveticus SBT2171 (LH2171) inhibited the proliferation and inflammatory cytokine production of primary immune cells in vitro, and alleviated collagen-induced arthritis (CIA) in mice, a model of human rheumatoid arthritis (RA). In this study, we newly investigated whether LH2171 could relieve the severity of experimental autoimmune encephalomyelitis (EAE)...

Bioactive carbohydrates are crucial in mediating essential biological processes, and their biosynthesis is an essential aspect to develop for a global view of their biological functions. Lactic acid bacteria display an array of diverse and complex carbohydrates and, therefore, are of particular interest. Here we present the identification of a novel exocellular polysaccharide structure and the ...