Fluid flow has a fundamental role in the performance of packed bed reactors. Some related issues, such as pressure drop, are strongly affected by porosity, so non-spherical particles are used in industry for enhancement or creation of the desired porosity. In this study, the effects of particle shape, size, and porosity of the bed on the hydrodynamics of packed beds are investigated with three ...

Many cells are constantly exposed to fluid mechanical forces generated by flowing blood, and wall shear stresses modulate aspects of their structure and function. However, the mechanisms for mechanotransduction of flow are not well understood. Here we report that TRPM7, which is both an ion channel and a functional kinase, is translocated within cells in response to laminar flow. After exposure...

Abstract. We investigate a monolithic algorithm to solve the problem of time dependent interaction between an incompressible viscous fluid and an elastic solid. The continuous formulation of the problem and its discretization is done in a monolithic way, treating the problem as one continuum. The Q2/P dis 1 finite elements are used for the discretization and an approximate Newton method with co...

Atherosclerosis preferentially occurs in areas of turbulent blood flow and low fluid shear stress, whereas laminar blood flow and high shear stress are atheroprotective. Inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha), stimulate expression of endothelial cell (EC) genes that may promote atherosclerosis. Recent findings suggest a steady laminar blood flow decreases EC apo...

PURPOSE To evaluate and compare the abilities of enhanced depth imaging (EDI) and high-penetration optical coherence tomography (HP-OCT) to visualize the deep optic nerve head (ONH) and deep parapapillary structures. METHODS Horizontal and vertical optic nerve images were obtained using EDI-OCT and HP-OCT, during the same visit, from 24 eyes of 12 patients with glaucoma. Three graders, using ...

In this paper, the effects of adding nanoparticles including Tio2 to a fluid media for purpose of free convection heat transfer improvement were analyzed. The free convection was assumed to be in laminar flow regime and the solutions and calculations were all done by the integral method. Water, as a Newtonian fluid, was considered the base fluid (water) and all the thermo physical properties of...