PURPOSE To analyze the amounts and distributions of nonsulfated and sulfated keratan sulfate (KS) and chondroitin/dermatan sulfate (CS/DS) disaccharides in the interface wound of human postmortem LASIK corneas in comparison with normal control corneas. METHODS Corneal stromal tissue samples from central and paracentral hypocellular primitive stromal interface scars of human LASIK corneas and ...

PURPOSE To compare changes in corneal nerve fibers and keratocyte density by confocal microscopy after laser-assisted in situ keratomileusis (LASIK) and laser epithelial keratomileusis (LASEK). DESIGN Prospective, nonrandomized comparative clinical trial. METHODS Fifty-six eyes of 28 patients who underwent LASIK and 52 eyes of 26 patients who underwent LASEK were included. Confocal microsco...

OBJECTIVES To determine the effect of hyperopic laser in situ keratomileusis (H-LASIK) on corneal integrity, by investigating relationships between proportionate corneal tissue ablated and refractive outcomes at 3 months. METHODS 18 eyes of 18 subjects treated with H-LASIK by Technolas 217c Excimer Laser were included in the study. Orbscan II Topography System was used to determine corneal vo...

OBJECTIVE To evaluate the efficacy and safety of laser-assisted in situ keratomileusis (LASIK) in patients with preoperative dry eye. METHODS We divided the 543 eyes that underwent LASIK into the following 3 groups: eyes with definite dry eye (DE group), with probable dry eye (PDE group), and without dry eye (NDE group). We evaluated visual outcome, dry-eye status, and complications. OUTCOM...

purpose: to determine the efficacy, safety, and stability of these techniques and some factors affecting refractive and visual outcomes in treated patients. methods: 236 lasik-treated eyes (122 patients) and 218 prk-treated eyes (112 patients) with myopia and myopic-astigmatism between -1.25 and -4 diopters (d) underwent refractive surgery over an 11 month period by a single surgeon. patients w...

To the Editor: During the past 3 years, several studies have suggested that small incision lenticule extraction (SMILE) is a promising alternative to LASIK for the correction of myopia. For this reason, we have read with great interest the article by Lin et al.1 about the comparison of the visual results after SMILE and femtosecond laser-assisted LASIK (FS-LASIK) for the treatment of myopia. Ho...

Background: To investigate the relationship between high-order aberration (HOA) changes and RCST/CT (residual corneal stroma thickness/corneal thickness) after femtosecond LASIK surgery.

PURPOSE To study the changes in posterior corneal elevation after laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) using Scheimpflug topography with the Pentacam anterior segment imaging system (Oculus, Inc.). SETTING Department of Ophthalmology, Albany Medical Center, and a private clinical practice, Albany, New York, USA. METHODS In this prospective study, 121 co...

PURPOSE To compare the outcomes of topography-guided and wavefront-optimized treatment in patients having laser in situ keratomileusis (LASIK) for myopia. SETTING Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India. DESIGN Prospective contralateral-eye case study. METHODS Patients had topography-guided LASIK in 1 eye and wavefront-optimized LA...

Title: Topography-Based Screening for Previous Laser in Situ Keratomileusis for Myopia and Hyperopia Purpose: To develop a screening tool based on corneal topography to detect previous myopic and hyperopic laser in situ keratomileusis (LASIK). Settings: Clinical data from three private clinics analyzed in a university setting. Methods: 476 topographies (Orbscan II, Bausch & Lomb) were randomly ...