PURPOSE To evaluate the safety and efficacy of laser in situ keratomileusis (LASIK) compared to photorefractive keratectomy (PRK) for the correction of low or moderate myopia (-0.50 to -6.00 D) at 6 months after surgery. METHODS The study population comprised a non-randomized consecutive series of 622 eyes of 392 patients who were treated with the Nidek EC-5000 excimer laser. LASIK was perfor...

PURPOSE To characterize the early ocular-surface changes or tear inflammatory-mediators levels following small-incision lenticule extraction (ReLEx smile) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK). METHODS Forty-seven myopic subjects were recruited for this prospective study. Fifteen underwent ReLEx smile and thirty-two underwent FS-LASIK. Corneal fluorescein (FL)...

PURPOSE To evaluate changes induced by standard laser in situ keratomileusis (LASIK) for hyperopia on total and corneal optical quality. METHODS Total and corneal aberrations were measured before and after standard hyperopic LASIK in 13 eyes (preoperative spherical equivalent refractive error +3.17 +/- 1.10 D). The Chiron Technolas 217C laser with PlanoScan was used. Total aberrations (measur...

purpose: to evaluate the correlation between corneal power and corneal horizontal white to white diameter in myopic patients scheduled for lasik surgery. methods: overall, in 840 eyes of 420 myopic subjects scheduled for lasik, horizontal white to white diameter and mean corneal power were obtained using orbscan ii. pearson correlation test and regression analysis were used to detect any correl...

PURPOSE To compare small incision lenticule extraction (SMILE) versus LASIK for post-refractive dry eye disease. DESIGN Prospective, comparative, nonrandomized clinical study. PARTICIPANTS Thirty patients scheduled for bilateral myopic SMILE and 30 age-, sex-, and refraction-matched patients scheduled for bilateral myopic LASIK were enrolled and followed for 6 months after the surgery. ME...

Purpose To compare two-year results of femtosecond laser assisted LASIK (femto-LASIK) and photorefractive keratectomy (PRK) in terms of astigmatism correction in patients with less than 2.0 diopters (D) of spherical error and more than 2.0 D of cylinder error. Methods In this retrospective study, data were extracted from 100 patient charts. The two study groups were matched by age, gender, an...

PURPOSE To determine the efficacy, stability, and predictability of refractive surgery for hyperopia using four different procedures: photorefractive keratectomy (PRK), laser in situ keratomileusis (LASIK), implantation of a phakic intraocular lens (PIOL), and removing the transparent lens with IOL implantation. METHODS We operated on 184 eyes with hyperopia; 56 eyes had less than +2.00 D (lo...

PURPOSE To investigate the effect of macrophage migration inhibitory factor (MIF) on corneal sensitivity after laser in situ keratomileusis (LASIK) surgery. METHODS New Zealand white rabbits were used in this study. A hinged corneal flap (160-µm thick) was created with a microkeratome, and -3.0 diopter excimer laser ablation was performed. Expressions of MIF mRNA in the corneal epithelial cel...

Aim: To investigate the repeatability and sensitivity of two commonly used sine wave patch charts for contrast sensitivity (CS) measurement in cataract and refractive surgery outcomes. Methods: The Vistech CS chart and its descendant, the Functional Acuity Contrast Test (FACT), were administered in three experiments: (1) Post-LASIK and age matched normal subjects; (2) Preoperative cataract surg...

BACKGROUND To evaluate the safety of besifloxacin ophthalmic suspension 0.6% when used in laser-assisted in situ keratomileusis (LASIK) prophylactic antibiotic regimens. METHODS Retrospective surveillance of LASIK surgery cases where besifloxacin ophthalmic suspension 0.6% or moxifloxacin ophthalmic solution 0.5% were prescribed as prophylactic medications. Surgeons from nine US surgical cent...