(1) Background: This study aimed to investigate the feasibility of using Maackia amurensis branch extract as a cosmetic ingredient with skin-whitening and antiwrinkle effects. (2) Methods: The effect M. was confirmed by investigating α-melanocyte-stimulating hormone (α-MSH)-induced melanin synthesis melanogenic protein expression in B16F1 cells. verified assessing matrix metalloproteinase (MMP)...