Traumatic and nontraumatic rhabdomyolysis can lead to acute renal failure (ARF), and acute alcohol intoxication can lead to multiple abnormalities of the renal tubules. We examined the effect of acute alcohol intoxication in a rat model of rhabdomyolysis and ARF. Intravenous injections of 5 g/kg ethanol were given to rats over 3 h, followed by glycerol-induced rhabdomyolysis. Biochemical parame...

Lead intoxication results in a disturbance of heme biosynthesis, its degree depending on the severity and duration of exposure to lead. A mild secondary, sideroblastic anemia is common; basophilic stippling may occur, especially in severe lead poisoning. Increased excretion in the urine of delta-aminolevulinic acid and coproporphyrin III may occur; porphobilinogen excretion is not usually incre...

Lead-containing cooking utensils, sometimes used in South Indian homes, and indigenous medications, widely used in India and increasingly in developed countries, may be responsible for lead intoxication in adults. We report chronic lead poisoning in five adult patients. Not all patients had abdominal colic, while dramatic weight loss, depression and encephalopathy were seen. Once recognized, le...

Lead intoxication is one of the most health hazards in humans at all ages. Lead impairs oxidant/antioxidant balance that can be partially responsible for the toxic effect of lead in the various organs of body especially cardiovascular system. The main objective of this study was to evaluate the effect of carvacrol as anti-oxidative agent on hypertension and some blood parameters in lead poisone...

background: lead still remains an important problem for poor, inner-city, ethnic minority children, with a particular emphasis on lead paint and dust. in egypt, there is no national survey about the prevalence of elevated blood lead level among children. objective: to assess the environmental lead level as well as to determine blood lead level among primary school children and find out its rela...

background: acute appendicitis is the most common surgical emergency of the childhood. its diagnosis is really challenging. a constellation of through history taking, physical examination, radiographic investigations, and laboratory analysis should be used to balance the risk of delayed operative intervention against the removal of a normal appendix. here a case with misdiagnosis of acute appen...

bachground: paraquat (pq) intoxication manifests with pulmonary edema and fibrosis, heart failure, hepatic failure, and sometimes convulsions. in severe cases, the patients may die within the early hours. at best conditions, the conventional therapeutic methods can only save less than 50% of the victims of intentional pq intoxication. the aim of this study was to evaluate the outcome of new the...

Previous reports have shown that blood lead levels in humans are associated with a polymorphic form of delta-aminolevulinate dehydratase (ALAD), an enzyme of heme biosynthesis that binds and is inhibited by lead. We hypothesized that ALAD levels may influence the distribution and accumulation of lead in the blood and target organs. To assess this, we studied strains of mice that differ in the n...

BACKGROUND Irrigation of closed body spaces may lead to substantial perioperative fluid and electrolyte shifts. A syndrome occurring during transurethral resection of prostate (TURP), and a similar syndrome described in women undergoing transcervical endometrial ablation (TCEA) are both characterised by a spectrum of symptoms which may range from asymptomatic hyponatraemia to convulsions, coma,...