Leishmaniasis is a major health problem worldwide, with several countries reporting cases of leishmaniasis resulting in loss of human life or a lifelong stigma because of bodily scars. The Middle East is endemic for cutaneous leishmaniasis, with countries like Syria reporting very high incidence of the disease. Despite several countries establishing national control programs for containing the ...

BACKGROUND Cutaneous leishmaniasis is a major health problem in Iran in spite of implementation of control program. This infectious disease caused morbidity in less than 27000 people in 2010. This study was set to determine some ecological aspects of sand flies in Fasa district, Fars Province, southern Iran during 2011-2012. METHODS A total of 4792 sand flies were captured by means of sticky ...

BACKGROUND & OBJECTIVES Sandflies are reported as the vectors of different kinds of leishmaniasis to human. There are foci of the disease in Iran. The aim of this study was to determine the fauna and species composition of sandflies to find the probable vectors of leishmaniasis in Nikshahr county, south-east of Iran, where cutaneous leishmaniasis is endemic. METHODS Sandflies were collected b...

Background.  Disseminated leishmaniasis (DL) is an emerging clinical form of American tegumentary leishmaniasis (ATL) that occurs mainly in Northeastern Brazil. This study describes 18 cases where DL has not yet been reported. Methods.  Disseminated leishmaniasis cases were extracted from ATL recorded cases between 1987 and March 2015. Disseminated leishmaniasis identification was based on ≥10 ...

BACKGROUND Pentavalent antimonials (SbV) are the first-line chemotherapy for American tegumentary leishmaniasis (ATL). There are, however, reports of the occurrence of treatment failure with these drugs. Few studies in Latin America have compared the response to SbV treatment in ATL caused by different Leishmania species. METHODS Clinical parameters and response to SbV chemotherapy were studi...

Background: Leishmaniasis, especially cutaneous leishmaniasis, is considered an important health problem in many parts of Iran including Kharve, Khorasan Razavi province. Cutaneous leishmaniasis is caused by various species of Leishmania, each having a different secondary host. Thus, identifying the parasites’ specie is of paramount importance for containment strategy planning. The morpho...

b a ckground: microbes particularly bacteria presenting in the gut of haematophagous insects may have an important role in the epidemiology of human infectious disease. m e t hods: the microbial flora of gut and surrounding environmental of a laboratory strain of phlebotomus papatasi , the main vector of zoonotic cutaneous leishmaniasis (zcl) in the old world, was investigated. biochemical reac...

Leishmaniasis is a disease caused by a malaria-like parasite called Leishmania in human and some species of animals. Detection of leishmaniasis has always been crucial for control and treatment of the disease. Different strategies have been approached for detection of leishmania. In this review methods used for detection of leishmania infection have been discussed and compared.

DNA sequencing and microsatellite analyses were performed to investigate the relationship of Sri Lankan cutaneous leishmaniasis isolates to known species of Leishmania. This identified L. donovani as the agent of Sri Lankan cutaneous leishmaniasis, and showed these parasites are closely related to those causing visceral leishmaniasis in the Indian subcontinent.