allergic airway inflammation is characterized by elaboration of cytokines and chemokines leading to recruitment of inflammatory leukocytes, predominantly eosinophils, to the airways. granulocyte macrophage colony stimulating factor (gm-csf) is generated in the lungs of human subjects with asthma in response to allergen challenge and is necessary for the development of allergen-induced bronchial...

purpose: to image leukocyte adherence to the vascular endothelium and extravasation into surrounding tissues in neovascularized corneas using acridine orange, a selective dna stain, in rats methods: corneal neovascularization was induced by placing two sutures in the cornea of one eye of 12 long-evans rats. one week later, acridine orange (4 mg/kg) was injected via the tail vein and the eyes we...

background:intraventricular hemorrhage is the most common intracranial hemorrhage in premature infants. the objective of this study was to investigate the relationship between intraventricular hemorrhage and blood leukocyte count. materials and methods:this was a cross-sectional simple sampling study conducted from the beginning of 2006 to 2010 in ali-asghar children’s hospital. inclusion crite...

BACKGROUND There are several reports demonstrating the role of CD8 T cells against Leishmania species. Therefore peptide vaccine might represent an effective approach to control the infection. We developed a rational polytope-DNA construct encoding immunogenic HLA-A2 restricted peptides and validated the processing and presentation of encoded epitopes in a preclinical mouse model humanized for ...

BBackground: We have previously reported that immunization with GRA 2 antigen of Toxoplasma gondii induces protective immunity in CBA /J (H2k) and BALB/c mice (H2d). We aimed to examine whether immunization of a distinct strain of rodent with recombinant dense granule antigens (GRA2) combined with monophosphorryl lipid A (MPL) adjuvant elicits protective immune response against T. gondii. Metho...

introduction: leukocytes causing a wide variety of side effects after transfusion are present in all blood products prepared by standard methods. as a consequence, the use of filter technology for leukoreduction has been widely practiced .according to aabb accreditation in 1996, leukoreduced blood components must contain less than 5×106 leukocytes per unit, but sometimes this value is higher ev...

background: the level of platelet volume (mpv) has been reported to be a laboratory marker in inflammatory cases. objectives: the aim of this study was to seek whether mpv has a role in the diagnosis of acute appendicitis. it was also aimed to show the relationship of mpv with leukocyte count and c-reactive protein (crp) level. materials and methods: this study was conducted via retrospective a...

The World Health organization has recommended childhood immunization with Teatuns vaccine (or TT containing vaccines) with a 5 doses schedule [1]. This included a 3 doses in infancy as DPT, followed by booster at 4-7 year and another dose at 12-15 years of age [1]. However, the national immunization schedule in Universal Immunization Program (UIP) in India, recommends at least 7 doses of Tetanu...

Each year, CDC's Advisory Committee on Immunization Practices (ACIP) reviews the recommended childhood and adolescent immunization schedule to ensure that it is current with changes in manufacturers' vaccine formulations and contains revised recommendations for the use of licensed vaccines, including those newly licensed. The recommended childhood immunization schedule for 2003 has remained the...