background and aims. the aim of this study was to evaluate the effect of different etching times on enamel color stability after immediate versus delayed exposure to colored artificial saliva (cas). materials and methods. human first premolars were divided into five groups of twenty. a colorimeter was used according to the cie system on the mid-buccal and mid-lingual surfaces to evaluate initia...

Vitamin D deficiency has been implicated as a risk factor for multiple sclerosis (MS), but how vitamin D metabolism affects MS pathophysiology is not understood. We studied the expression of vitamin D receptor (VDR) and related enzymes, including 1,25(OH)(2)D-24-hydroxylase (24-OHase; CYP24A1) and 25(OH)D-1α-hydroxylase (CYP27B1), in CNS tissues of 39 MS patients and 20 controls and in primary ...

CONTEXT Atopic dermatitis is a chronic inflammatory skin disease resulting from interactions between environmental and genetic factors. Recent studies link atopic dermatitis with asthma and with eosinophilic esophagitis. CASE REPORT Based on this association, we investigated by indirect immunofluorescence the immunoreactivity patterns on monkey esophagus substrate utilizing the serum of a pat...

AIM To evaluate the therapeutic effect of netrin-4 on the early acute phase of inflammation in the alkali-burned eye. METHODS Eye drops containing netrin-4 or phosphate buffered saline (PBS) were administered to a alkali-burn-induced corneal acute inflammatory model four times daily. The clinical evaluations, including fluorescein staining and inflammatory index, were performed on day 1, 4 an...

By LEONARD S. KAPLOW T HE RESULTS of previous studies’8 on the histochemical localization of alkaline phosphatase activity in cells of blood and bomie marrow have been varied and contradictory. All such studies, except that of Vercauteren,8 were based on the Gomori-Takamutsu procedure.” ‘#{176}Numerous investigators”9 have shown that this procedure may produce false staimiing of nuclei and othe...

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 52-year-old woman with a history of hepatocellular carcinoma with bone metastasis (T6, L5-S1) was referred for pancytopenia after undergoing radiation therapy and transarterial chemoembolization. Splenomegaly and compact lipiodol retention in liver segment...

We recently identified several individuals carrying a missense mutation (G329A; Arg(110)-Gln) in the FUT7 gene encoding fucosyltransferase VII. This enzyme is involved in the biosynthesis of the sialyl Lewis x (Le(x)) epitope on human leukocytes, which has been identified as an important component of leukocyte ligands for E- and P-selectin. No enzyme activity was measurable in expression studie...

Cell adhesion molecules of the Ig superfamily play an important role in embryonic development. It has recently been shown that JAM-A, a member of this family expressed at endothelial and epithelial tight junctions, is involved in platelet activation, leukocyte transmigration, and angiogenesis. Here I determine the expression pattern of the JAM-A gene during embryogenesis using transgenic mice e...