BACKGROUND Several monoclonal antibodies (mAbs) recognising Lewis(y), such as BR96, have reached the clinic but have failed to show good anti-tumour responses with an acceptable level of toxicity. No Lewis(b) mAbs have been trialled in patients. In this study we compare the specificity of three mAbs; BR96 (Lewis(y)), 2-25 LE (Lewis(b)) and 692/29 that recognises a unique facet of both Lewis(y) ...

A dominant factor in determining the burning rate of a premixed turbulent flame is the degree to which the flame front is wrinkled by turbulence. Higher turbulent intensities lead to greater wrinkling of the flame front and an increase in the turbulent burning rate. This picture of turbulent flame dynamics must be modified, however, to accommodate the affects of variations in the local propagat...

Considering the high incidence and mortality rate of esophageal cancer in some areas of the country, and its diagnosis at a time of advanced growth, this study was carried out to determine the predisposing factors and the most effective and applicable surgical procedure. In this descriptive study, 158 patients (95 males and 63 females) with esophageal cancer were studied. They referred to Shoh...

This work deals with exploring some empirical scales of nucleophilicity. We have started evaluating the experimental indices of nucleophilicity proposed by Legon and Millen on the basis of the measure of the force constants derived from vibrational frequencies using a probe dipole H-X (X = F,CN). The correlation among some theoretical parameters with this experimental scale has been evaluated. ...

Lewis acidic zeolites are used to synthesize unsaturated dicarboxylic acid esters via aldol condensation of keto esters. Hafnium-containing BEA (Hf-BEA) zeolites catalyze the condensation of ethyl pyruvate into diethyl 2methyl-4-oxopent-2-enedioate and diethyl 2-methylene-4oxopentanedioate (an itaconic acid ester analogue) with a selectivity of ca. 80% at ca. 60% conversion in a packed-bed reac...

more fully the inheritance of tooth size in British families. Though twin studies have established a high genetic component in tooth size (Lundstrom, 1948; Osborne, Horowitz, and De George, 1958), few family studies have been undertaken to elucidate the matter further. The studies of Hohl (1934) and Martin (1934) were among the first but used relatively small samples. They calculated both paren...

We prove generalized versions of some conjectures of Joel Lewis on the number of alternating permutations avoiding certain patterns. Our main tool is the perhaps surprising observation that a classic bijection on pattern avoiding permutations often preserves the alternat-

of all substances, great fields of equilibria hitherto unsuspected, in which the individual states differ from one another with respect to the new variable, the number of photons. If such a necessity arises and the law of conservation of photons can be established, it may be necessary to revise still further our ideas of thermal radiation, for in that case it would be doubtful whether what is k...

THE LEWIS blood group antigens Lea and Leb have been found on red blood cells (RBCs), in secretions and fluids such as saliva, alimentary tract juice, and urine, and in various tissues including renal tubular cells, collecting ducts, urothelium, and ductal or mucosal epithelium of the sweat glands, salivary glands, gastrointestinal tract, pancreas, uterus, cervix, and breast. l .s Hepatic bile ...