نتایج جستجو برای: lifetime cancer risk
تعداد نتایج: 1784804 فیلتر نتایج به سال:
BACKGROUND Accurate risk (penetrance) estimates for associated phenotypes in carriers of a major disease gene are important for genetic counselling of at-risk individuals. Population-specific estimates of penetrance are often needed as well. Families ascertained from high-risk disease clinics provide substantial data to estimate penetrance of a disease gene, but these estimates must be adjusted...
Using a pre-post test design with a baseline, laboratory, and a 6-month follow-up, we communicated women's objective breast cancer risks, based on the Gail Model, using two formats: (a) range of risks (e.g., risk of breast cancer can be as low as 1% and as high as 5%); and (b) as a point estimate (e.g., your risk of breast cancer is 3%). We examined how these presentations individually and join...
Introduction: 1,3-Butadiene is a carcinogenic compound that can be emitted to the atmosphere from several sources like petrochemical industry. One way to determine the level of carcinogenic and health effects of respiratory exposure to pollutants in the workplace is to use risk assessment methods. The aim of this study was to comparative assessment of carcinogenic risk of respiratory exposure t...
There is an increasing need for accurate prediction methods of assessing individual risk for breast cancer for both clinical and research purposes. The purpose of this study is to compare the Gail and Claus model risk estimates of breast cancer among women with a family history of breast cancer. This study presents risk estimates from two models of breast cancer risk in 491 women 18 to 74 years...
The series of ordered mutations that cause a specific cell to become cancerous is modeled so that the fraction of a risk population (e.g. White men) that has developed a specific cancer (e.g. melanoma) at any age can be calculated. The saturated model constructed and solved here is isomorphic to the physical model describing an ordered chain of radioactive nuclei decays with the exception that ...
background: many public health agencies rank residential radon exposure as the second leading cause of lung cancer after cigarette smoking. it has been shown that the risk coefficient for lung cancer is higher for children than that for adults. therefore, indoor radon measurements were carried out in the elementary schools of tulkarem province, west bank, palestine. materials and methods: two h...
BACKGROUND Physical inactivity is a potentially modifiable breast cancer risk factor. Because few data on this relationship exist for black women, we examined the relationship between breast cancer risk and lifetime and time- or age-specific measures of recreational exercise activity among white women and among black women. METHODS The Women's Contraceptive and Reproductive Experiences Study ...
Key Findings Crude rates depict the true magnitude of the risk as an average measure at the total population level. However, they are heavily affected by the respective age composition of the populations being compared. Once standardised for age composition, the rates become comparable. However, the standardised rates are hypothetical. In all cancer incidence for example, they are not the true ...
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