The effect of 96 h exposure the goldfish Carassius auratus to two different types bioplastic particles, originating from commercial shopping bag (Bag, ~5 mm) and polylactic acid-based (PLA) cup (Cup, ≤5 mm), petroleum-based polyamide particles (PA, 0–180 µm) was studied. All were studied as virgin after simulated UV-degradation (at concentration 30 mg L−1). experiments conducted according OECD ...

Oxidative stress is defined as a condition in which the balance between production of reactive oxygen species (ROS) and antioxidant defense system gets disturbed causes free radical induced diseases. The current research was aimed to carrying out quantification phytochemicals different parts explores activities ethanolic extracts leaf (CFL), seed (CFS), bark (CFB) show their therapeutic importa...

In rats, lisdexamfetamine (LDX) induces manic-like behaviors such as hyperlocomotion and increases in appetitive 50-kHz ultrasonic vocalizations (USV), which are prevented by antimanic drugs, lithium. Inhibition of glycogen synthase kinase 3 beta (GSK3?) antioxidant activity have been associated with effects. Thus, the aim present study was to evaluate possible antimanic-like effects andrograph...

Introduction and Aim: Multiple sclerosis (MS) is a complex neurological condition might emerge as result ofcomplex combination of genetic risk factors with environmental triggers, including oxidative stress. in this study we aimed to evaluate the effects oral Crocin on stress patients MS. 
 Materials Methods: Adjunct standard treatment, group (20 patients) received 30-mg/day (15 mg twice d...

Iron overload is known to occur in the West European and American population due to the consumption of iron-rich diets. On the other hand, genetic disorders leading to iron overload are also known. Iron overload leads to increased peroxidation and disruptive disintegration of lipid-rich membranes, and predisposes humans for an enhanced risk of cancer induction. In experimental animals iron ...

Oxidative processes, especially lipid peroxidation (LPO), are assumed to increase during ageing. In an attempt to provide experimental evidence for this assumption lemon balm plants (Melissa officinalis L.) of different age and location were analyzed for oxidatively caused changes in the etheric oil composition. The investigation revealed that the caryophyl­ lene oxide (CarO) content of lemon b...

elevated amounts of free radicals due to ionizing radiation have damaging effects on the body. h2-receptor antagonists have potential oxygen radical scavenging properties. we tried to determine the effects of two h2-receptor antagonists (cimetidine and ranitidine) on lipid peroxidation (lpo) and lipid profile (lp) in plasma and liver of γ-irradiated (1gy/day for 3 days) balb/c mice. the control...

In several human diseases, such as cancer and neurodegenerative diseases, the levels of reactive oxygen species (ROS), produced mainly by mitochondrial oxidative phosphorylation, is increased. In cancer cells, the increase of ROS production has been associated with mtDNA mutations that, in turn, seem to be functional in the alterations of the bioenergetics and the biosynthetic state of cancer c...

P. niruri has been reported to possess antidiabetic and kidney protective effects. In the present study, the phytochemical constituents and in vitro antioxidant activity of P. niruri leaf aqueous extract were investigated together with its effect on oxidative stress and antioxidant enzymes levels in diabetic rat kidney. Results. Treatment of diabetic male rats with P. niruri leaf aqueous extrac...

Effect of aqueous extracts of Ocimum sanctum and Camellia sinensis on restraint stress-induced oxidative damage in the central nervous system (CNS) of R. norvegicus were evaluated in terms of lipid peroxidation (LPO), reduced glutathione (GSH), superoxide dismutase (SOD) and catalase (CAT). Restraint stress was used for 3h/day for 6 days consecutively, caused a significant elevation in LPO and ...