Wistar rats were given a diet with 8% sodium chloride to induce hypertension and subsequently sacrificed. Glycine max powder was used reduce atenolol’s side effects during the trial. Thirty divided into five groups tested over eight weeks. Rats’ blood pressure (BP) measured tail-cuff NIBP monitor. Biochemical markers like TG, TC, HDL, LDL, VLDL, alanine transferase, aspartate lipid peroxide (LP...

Two natural flavonoids, quercetin and isorhamnetin 3-O-acylglucosides, were examined for their inhibitory influence on the in vitro production and release of reactive oxygen species in polymorphonuclear neutrophils (PMNs). The generation of superoxide radical, hydrogen peroxide and hypochlorous acid were measured by, respectively, cytochrome c reduction, dichlorofluorescin oxidation and taurine...

The mechanism of lipid peroxidation catalyzed by bleomycin (BLM)-iron (Fe) complexes has been studied in vitro using sodium linoleate as a substrate. BLM-Fe(II)-O2 and BLM-Fe(III) complexes catalyze lipid peroxidation concomitantly with singlet oxygen evolution. The results from spin trapping methods and gas chromatography-mass spectroscopy (GCMS) analyses suggest that the initial step of lipid...

antioxidant active packaging is one of the active packaging that prevents of lipid oxidation by releasing antioxidant during storage of food. in recent years the use of natural antioxidant instead of the synthetic variety in these packaging has been considered. the aim of this study was evaluating the performance of polymeric film coated with natural antioxidant (rosemary extract) to prevent li...

Silymarin ‘milk thistle’ (Silybum marianum) plant, has been used for years treatment of different diseases such as liver and gallbladder disorders, protecting against snake bite insect stings, mushroom poisoning alcohol abuse. antioxidant, anti-lipid peroxidative, antifibrotic, anti-inflammatory, immunomodulatory, regeneration activities. The cardioprotective activities silymarin were primarily...

Anticancer therapy with doxorubicin (DOX) and other quinone anthracyclines is limited by severe cardiotoxicity, reportedly because semiquinone metabolites delocalize Fe(II) from ferritin and generate hydrogen peroxide, thereby promoting hydroxyl radical formation and lipid peroxidation. Cardioprotective interventions with antioxidants or chelators have nevertheless produced conflicting results....

the present experiment was designed to access the effects of methylmercury chloride ( mehgcl) on antioxidant status, protein concentration, lipid peroxidation and hydroperoxidation in brain parts, spinal cord, lung, heart and pancreas of rats. twenty male wistar rats (3 months old) were divided in saline controls (c) and mehgcl-treated group (mmc). treated rats were intoxicated with mmc at a do...