نتایج جستجو برای: lipl32

تعداد نتایج: 165  

2015
Gregory T. Robbins Beth L. Hahn Karen V. Evangelista Lavinia Padmore Patrick S. Aranda Jenifer Coburn

Pathogenic spirochetes of the genus Leptospira are the causative agents of leptospirosis, a zoonotic infection that occurs globally. The bacteria colonize the renal proximal tubules of many animals and are shed in the urine. Contact with the urine, or with water contaminated with the urine of infected animals can cause infection of new host animals, including humans. Mechanisms of colonization ...

2017
Irina N Riediger Robyn A Stoddard Guilherme S Ribeiro Sueli M Nakatani Suzana D R Moreira Irene Skraba Alexander W Biondo Mitermayer G Reis Alex R Hoffmaster Joseph M Vinetz Albert I Ko Elsio A Wunder

BACKGROUND With a conservatively estimated 1 million cases of leptospirosis worldwide and a 5-10% fatality rate, the rapid diagnosis of leptospirosis leading to effective clinical and public health decision making is of high importance, and yet remains a challenge. METHODOLOGY Based on parallel, population-based studies in two leptospirosis-endemic regions in Brazil, a real-time PCR assay whi...

2017
André Alex Grassmann Jéssica Dias Souza Alan John Alexander McBride

Leptospirosis is the most widespread zoonosis in the world and a neglected tropical disease estimated to cause severe infection in more than one million people worldwide every year that can be combated by effective immunization. However, no significant progress has been made on the leptospirosis vaccine since the advent of bacterins over 100 years. Although protective against lethal infection, ...

2009
Monica L Vieira Daniel C Pimenta Zenaide M de Morais Silvio A Vasconcellos Ana L.T.O Nascimento

Leptospirosis is a worldwide zoonotic infection of human and veterinary concern. Caused by pathogenic spirochetes of the genus Leptospira, the disease presents greater incidence in tropical and subtropical regions. The identification of proteins that could be involved in the bacteria host interactions may facilitate the search for immune protective antigens. We report the proteomic analysis of ...

2017
Patrícia A E Abreu Antonio C Seguro Daniele Canale Ana Maria G da Silva Larissa do R B Matos Tatiane B Gotti Denize Monaris Denise A de Jesus Sílvio A Vasconcellos Thales de Brito Antonio J B Magaldi

Acute kidney injury (AKI) from leptospirosis is frequently nonoliguric with hypo- or normokalemia. Higher serum potassium levels are observed in non-survivor patients and may have been caused by more severe AKI, metabolic disarrangement, or rhabdomyolysis. An association between the creatine phosphokinase (CPK) level and maximum serum creatinine level has been observed in these patients, which ...

Journal: :Transboundary and Emerging Diseases 2023

Leptospirosis is a zoonosis with ubiquitous distribution caused by spirochetes belonging to the genus Leptospira sp., endemic mainly in tropical and subtropical regions of world capable infecting domestic animals, free-living humans. Although well documented terrestrial animals humans, little information available on its impact marine animals. There are few studies assessing cetaceans’ health s...

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