Liver cirrhosis is recognized as being the consequence of immune-mediated hepatocyte damage and repair processes. However, the regulation of these immune responses underlying liver cirrhosis has not been elucidated. In this study, we used GEO datasets and bioinformatics methods to established coding and non-coding gene regulatory networks including transcription factor-/lncRNA-microRNA-mRNA, an...

BACKGROUND A single nucleotide polymorphism (SNP) of patatin-like phospholipase domain-containing 3 (PNPLA3) genes (rs738409) is associated with the severity of fibrosis and cirrhosis in patients with fatty liver disease. However, in a small group of Italian patients, there was no significant correlation between the rs738409 SNP and hepatitis B virus (HBV) infection-associated liver cirrhosis. ...

Liver cirrhosis is the fatal end stage of various chronic liver diseases. One of the most important causes of liver cirrhosis appears to be an impaired proliferative capability of hepatocytes caused by continuous hepatic damage. Hepatocyte growth factor (HGF) and its specific receptor, c-Met, play a pivotal role in hepatocyte proliferation. However, the relationship between the proliferative ca...

AMA Sun H, Zhou Y, Shu C, Huang T, Xiao J. Effects of gastrointestinal endoscopy at different time points on diagnosis and treatment upper bleeding in patients with liver cirrhosis. Videosurgery Other Miniinvasive Techniques/Wideochirurgia i inne techniki małoinwazyjne. 2023. doi:10.5114/wiitm.2023.130325. APA Sun, H., Zhou, Y., Shu, C., Huang, T., & Xiao, (2023). https://doi.org/10.5114/wiitm....

Purpose The CirCom score has been developed from Danish data as a specific measure of comorbidity for cirrhosis to predict all-cause mortality. We compared its performance with the Charlson Comorbidity Index (CCI) in an English cirrhosis population. Patients and methods We used comorbidity scores in a survival model to predict mortality in a cirrhosis cohort in the Clinical Practice Research ...

Aim The objective of this study was to determine the epidemiologic characteristics of patients with liver cirrhosis. Background Liver cirrhosis is an end-stage condition of chronic liver disease. Liver disease is an important cause of morbidity and mortality worldwide. Methods In this cross-sectional study, demographic and epidemiologic characteristics of 203 patients with liver cirrhosis w...

Patients with liver diseases have a higher risk of hemostatic disorders. Meanwhile, despite well-established opinion on low thromboses in cirrhosis, thromboembolic events cannot be totally ruled out these patients. Increased risks thrombotic and venous thromboembolism cirrhosis are accounted for by external (immobilization, surgeries, infections, comorbidities) internal factors (reduced synthes...

The aim of this work is to analyze quantitative data magnetic resonance ASL-perfusion the liver at admission and follow up patients with viral cirrhosis. study included 34 cirrhosis: 23 (67.6 %) men 11 (32.4 women. All subjects underwent abdominal ultrasound Dopplerography vessels, shear wave elastography, Arterial spin Labeling (ASL) — Perfusion by imaging. Post-processing images was carried o...

BACKGROUND Liver cirrhosis is a major yet largely preventable and underappreciated cause of global health loss. Variations in cirrhosis mortality at the country level reflect differences in prevalence of risk factors such as alcohol use and hepatitis B and C infection. We estimated annual age-specific mortality from liver cirrhosis in 187 countries between 1980 and 2010. METHODS We systematic...