Being the biggest inner organ of humans, the liver contributes decisively to metabolism. Hereby, liver activities result from reactions on ingestion and digestion and are assumed to influence the acoustical properties of the liver tissue. In this work we present initial results of the investigation of aforementioned reactions by observing the liver in-vivo with ultrasound during several hours. ...

PURPOSE To assess the quality of the arterial input function (AIF) reconstructed using a dedicated pre-bolus low-dose contrast material injection imaged with a high temporal resolution and the resulting estimated liver perfusion parameters. MATERIALS AND METHODS In this IRB-approved prospective study, 24 DCE-MRI examinations were performed in 21 patients with liver disease (M/F 17/4, mean age...

Background Cholestatic jaundice in infancy is always pathologic and mainly caused by biliary atresia (BA), and neonatal hepatitis (NH). The early discrimination of both conditions is critical for the outcome of BA. We aimed to assess different non-invasive diagnostic tools in differentiating BA from NH. Materials and Methods Forty infants (25 boys, 15 girls) with cholestatic jaundice and final...

Background: Ethinylestradiol (EE) has induced cholestasis and hepatotoxicity in animal studies through reducing bile acid uptake by hepatocytes and induce of oxidative stress. Pentoxifylline (PTX) is a drug that by inhibition of release or transcription of proinflammatory cytokine cause prevents oxidative stress of liver cell and reduction of damage. We aimed to evaluate the effects of pentoxif...