Perceptual learning was used as a tool for studying motion perception. The pattern of transfer of learning of luminance- (LM) and contrast-modulated (CM) motion is diagnostic of how their respective processing pathways are integrated. Twenty observers practiced fine direction discrimination with either additive (LM) or multiplicative (CM) mixtures of a dynamic noise carrier and a radially isotr...

The type I interferon (IFN) activated transcriptional response is a critical antiviral defense mechanism, yet its role in bacterial pathogenesis remains less well characterized. Using an intracellular pathogen Listeria monocytogenes (Lm) as a model bacterial pathogen, we sought to identify the roles of individual interferon-stimulated genes (ISGs) in context of bacterial infection. Previously, ...

Central nervous system (CNS) metastasis from breast cancer may be characterized as either parenchymal brain metastasis (BM) or leptomeningeal (LM) metastasis. BM are much more common (about 80% of all CNS metastases), and have been more extensively studied than LM. CNS metastasis in breast cancer has been associated with reduced overall survival, with the shortest survival generally observed in...

The purpose of this paper is to describe string topology from the viewpoint of Chen’s iterated integrals. Let M be a compact closed oriented d-manifold and LM be the free loop space of M , the set of unbased smooth maps from S to M . Let H∗(LM) be the homology of the free loop space shifted by the dimension of the manifold i.e. H∗(LM) = H∗+d(LM). Chas and Sullivan found the product on H∗(LM) wh...

CONTEXT A 2001 Agency for Healthcare Research and Quality Evidence Report on patient safety addressed point-of-care limited ultrasonography guidance for central venous cannulation and strongly recommended real-time, dynamic guidance for all central cannulas. However, on the basis of one limited study, the report dismissed static assistance, a "quick look" with ultrasound to confirm vein locatio...

Low protein intake can lead to declined lean mass (LM) in elderly. We examined the associations of total protein (TP), animal protein (AP) and plant protein (PP) intakes with LM. The association of TP intake with LM change was further evaluated according to weight change status. This cross-sectional and prospective cohort study included 554 women aged 68 (sd 1·9) years from the Osteoporosis Ris...

We have determined by means of first principles quasiharmonic calculations the elastic constants and acoustic velocities of MgSiO3 perovskite, the most abundant mineral of the Earth's lower mantle (LM), at pertinent pressures and temperatures. Using these results, along with the effects of low concentration iron alloying and the thermoelasticity of the most important secondary LM phase, MgO, we...

We have selected piperaquine (PQ) and lumefantrine (LM) resistant Plasmodium berghei ANKA parasite lines in mice by drug pressure. Effective doses that reduce parasitaemia by 90% (ED(90)) of PQ and LM against the parent line were 3.52 and 3.93 mg/kg, respectively. After drug pressure (more than 27 passages), the selected parasite lines had PQ and LM resistance indexes (I(90)) [ED(90) of resista...

Text corpus size is an important issue when building a language model (LM). This is a particularly important issue for languages where little data is available. This paper introduces an LM adaptation technique to improve an LM built using a small amount of task-dependent text with the help of a machine-translated text corpus. Icelandic speech recognition experiments were performed using data, m...