BACKGROUND Understanding the mechanisms of drug resistance can facilitate better management of antiretroviral therapy, helping to prevent transmission and decrease the morbidity and mortality of people living with HIV/AIDS. However, there is little data about transmitted drug resistance and acquired drug resistance for HIV/AIDS patients in Shanghai. METHODS A retrospective cohort study of HIV...

The oil and gas industry has moved towards Load and Resistance Factor Design through API RP2A LRFD and the recently published international standard, ISO-19902, for design of fixed steel offshore structures. The ISO 19902 is intended to provide a harmonized design practice that offers a balanced structural fitness for the purpose, economy and safety. As part of an ongoing work, the reliability ...

A DISCUSSION OF THE HEMODYNAMICS of any circulation, and that of the pulmonary circulation in particular, must be concerned with three factors: (1) the flow through the circulation, which in the case of the lung is also the cardiac output; (2) the resistance to flow through the vas-cular bed, which is primarily a function of the number and diameter of resistance vessels , and to a lesser degree...

This study aims to undertake a statistical study to evaluate the accuracy of nine models that have been previously proposed for estimating the ultimate resistance of plate girders subjected to patch loading. For each model, mean errors and standard errors, as well as the probability of underestimating or overestimating patch load resistance, are estimated and the resultant values are compared o...

BACKGROUND Drug resistance to nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), and protease inhibitors (PIs) has been associated with loss of viral suppression measured by a rise in HIV-1 RNA levels, a decline in CD4 cell counts, persistence on a failing treatment regimen, and lack of adherence to combination antiretroviral therapy. ...

the welding in cold formed areas is not only an open question for statically loaded sections (brittle fracture) but also for dynamically loaded structures (fatigue resistance). a lot of structures are subjected to dynamic loadings and unfortunately very little information about the influence of welding in the cold formed areas on fatigue resistance is available. in order to establish the fatigu...

Objective: Introduction of fiber-reinforced composites (FRC) greatly enhanced the restoration of fractured anterior teeth. The purpose of this study was to assess the effect of fiber reinforcement on fracture resistance of incisal edge composite restorations of variable thicknesses. Methods: Forty extracted sound human maxillary incisors were divided into four groups of 10. Incisal reduction wa...