Objective (s): Bacterial infection is an important cause of delayed wound healing. Staphylococcus aureus (S. aureus) is the main agent causing these infections. Zinc Oxide (ZnO) nanoparticles have antibacterial activity and also accelerate the wound healing process. The aim of the present study is to evaluate the effect of ZnO nanoparticles on bacterial load reduction of the wound infection.  M...

Due to the ever-growing load, especially peak load, the increase in the capacity of plants is inevitable for the response to this growth. Peak load causes increases in customer costs and vast investments in generating and transmission parts. Therefore, restructuring in the electrical industry, competition in the electrical market and Demand Response Programs (DRPs) are of special importance in ...

Electric distribution system planning is to provide an economic expansion plan to meet the future demands in its territory. A forecast of the future electric demand and its geographic distribution is a prerequisite for distribution planning. The quality and accuracy of this forecast have large influence on the quality of the electrical distribution system planning. Spatial load forecasting emer...

Previously, we showed in Leishmania infections that extrinsic insulin-like growth factor (IGF)-I favored Leishmania proliferation and leishmaniasis development. In this study, the interaction of intrinsically expressed IGF-I and Leishmania (Leishmania) major in macrophages was addressed, and a key finding was the observation, using confocal microscopy, of the co-localization of IGF-I and parasi...

Genetic effects are often overlooked in endangered species monitoring, and populations showing positive growth are often assumed to be secure. However, the continued reproductive success of a few individuals may mask issues such as inbreeding depression, especially in long-lived species. Here, we test for inbreeding depression in little spotted kiwi (Apteryx owenii) by comparing a population fo...

The risk of extinction faced by small isolated populations in changing environments can be reduced by rapid adaptation and subsequent growth to larger, less vulnerable sizes. Whether this process, called evolutionary rescue, is able to reduce extinction risk and sustain population growth over multiple generations is largely unknown. To understand the consequences of adaptive evolution as well a...

The highly conserved insulin/insulin-like growth factor (IGF) signaling (IIS) pathway regulates metabolism, development, lifespan and immunity across a wide range of organisms. Previous studies have shown that human insulin ingested in the blood meal can activate mosquito IIS, resulting in attenuated lifespan and increased malaria parasite infection. Because human IGF1 is present at higher conc...

Acne in adults is a chronic, increasingly common disease, especially among women. It differs in pathogenesis and clinical presentation from adolescent acne. Acne in adults is associated with Western diet, defined as high consumption of milk, high glycemic load and high calorie intake. Metabolic signals of this diet result in a significant increase in insulin/insulin growth factor 1 serum level ...

OBJECTIVE: This study was designed to determine whether living in a neighborhood in which poverty levels increase across adolescence is associated with heightened levels of allostatic load (AL), a biological composite reflecting cardiometabolic risk. The researchers also sought to determine whether receipt of emotional support could ameliorate the effects of increases in neighborhood poverty on...

OBJECTIVE: This study was designed to determine whether living in a neighborhood in which poverty levels increase across adolescence is associated with heightened levels of allostatic load (AL), a biological composite reflecting cardiometabolic risk. The researchers also sought to determine whether receipt of emotional support could ameliorate the effects of increases in neighborhood poverty on...