Peering between Content Delivery Networks (CDNs) endeavors to ensure that each user is served by an optimal Web server in terms of network cost, even under heavy load conditions. Therefore, a dominant factor for the success of peering between CDNs is to perform load distribution to handle highly skewed loads. In this paper, our approach for dynamic load distribution adopts a request-redirection...

Asymmetric transverse-load characteristics and the polarization dependence of long-period fiber gratings (LPFGs) written by high-frequency CO(2) laser pulses are investigated in detail. It is demonstrated that the resonant wavelength is dependent on the direction of the applied force and on the polarization state of the input light; however, the coupling strength is independent of these paramet...

This paper discusses power flow control by use of controllable series devices. Through a sensitivity based method the control variables, e.g. series capacitor reactances or phase shifter angles, can be calculated quickly and accurately to obtain desired line flows within the load flow sensitivity boundaries. This method is applied to realistic power flow control scenarios in a simple power system.

The impetus for the present report is the evaluation of competing claims of two classes of working memory models: Memory systems models hold working memory to be supported by a network of prefrontal cortex (PFC)-based domain-specific buffers that act as workspaces for the storage and manipulation of information; emergent processes models, in contrast, hold that the contributions of PFC to worki...

The main purpose of this research is to determine the generation quantity of each generator in a power system. In this way, not only will the electricity demanded by the system be supplied, but the cost of fuel along with the level of pollution can be minimized. Obviously, calculation of the optimal layout of power plants with the aim of minimizing fuel costs and pollutants level contributes to...

Background. In order to minimize overtraining, a reliable method is required to analyze training loads. Objectives. The objective of this study was to see if session Rate of Perceived Exertion (sRPE) is a valuable tool for tracking changes in perceived training load and strain among Malaysia rugby 15-a-side players during preparation for a significant game. Methods. Twenty-eight (n=28) elite ...

To the Editor, On the other hand, the effects of length-dependent activation on myocardial function manifest significantly later, I appreciate the excellent points raised by Leite-Moreira et occurring several minutes after the initial change in muscle al. regarding my manuscript examining the load sensitivity length [6,7]. This is well beyond the time period examined of left ventricular (LV) re...

To the Editor, On the other hand, the effects of length-dependent activation on myocardial function manifest significantly later, I appreciate the excellent points raised by Leite-Moreira et occurring several minutes after the initial change in muscle al. regarding my manuscript examining the load sensitivity length [6,7]. This is well beyond the time period examined of left ventricular (LV) re...

Tumor mutation load (TML) has been proposed as a biomarker of patient response to immunotherapy in several studies. TML is usually determined by tumor biopsy DNA (tDNA) whole exome sequencing (WES), therefore TML evaluation is limited by informative biopsy availability. Circulating cell free DNA (cfDNA) provided by liquid biopsy is a surrogate specimen to biopsy for molecular profiling. Neverth...

This paper proposes a MOSFET-only, 20pA, 780ppm/oC current reference that consumes 23pW. The ultra-low power circuit exploits subthreshold-biased MOSFETs and a complementary-to-absolute temperature (CTAT) gate voltage to compensate for temperature dependency. The design shows low supply voltage sensitivity of 0.58%/V and a load sensitivity of 0.25%/V.